Relationship between short sleep duration and cardiovascular risk factors in a multi-ethnic cohort - the helius study
Relationship between short sleep duration and cardiovascular risk factors in a multi-ethnic cohort - the helius study
复制标题
DOI：
10.1016/j.sleep.2015.08.014
复制
发表时间：
2015-12-01
期刊：
影响因子：
4.8
通讯作者：
Agyemang, Charles
中科院分区：
文献类型：
--
作者：
Anujuo, Kenneth;Stronks, Karien;Agyemang, Charles
背景和目的：本研究的目的是调查短睡眠时间和心血管疾病（CVD）风险因素之间的关联，包括高血压，糖尿病，肥胖和血脂在不同种族群体（南亚裔缅甸人，非洲裔缅甸人，加纳人，土耳其人，马达加斯加人和荷兰人）生活在荷兰。社会经济地位（SES）和生活方式因素的贡献也被检查到这个association.Method：共12,805名参与者（年龄18 - 70岁）从多种族健康生活在城市环境（HELIUS）队列。短睡眠时间定义为<7小时/夜。使用患病率（PR）评估短睡眠与CVD危险因素之间的关联，沿着SES和生活方式因素的贡献。在六个种族中的四个中，睡眠不足与肥胖显著相关，社会人口统计学调整的PR为1.45（95% CI，1.07 - 1.95），南亚裔缅甸人为1.21（1.01 - 1.44），非洲裔缅甸人为1.25（1.09 - 1.43），土耳其人为1.16（1.04 - 1.29）。睡眠不足与糖尿病在非洲人（1.45，1.14 - 1.84），土耳其人（1.59，1.26 - 2.02）和马达加斯加人（1.29，1.02 - 1.63）显着相关。相比之下，其他心血管风险因素与睡眠不足之间的关联在大多数种族群体中并不显著，除了与荷兰人和土耳其人的高血压，以及南亚人的血脂异常（降低高密度脂蛋白胆固醇和甘油三酯）和马达加斯加人（升高总胆固醇）的关联。SES和生活方式的因素贡献不大，观察association.Conclusion：研究结果表明，睡眠不足与肥胖和糖尿病在大多数种族群体。其他风险因素的关联在不同种族群体之间存在差异。需要进一步研究以确定可能导致观察到的人群差异的潜在因素。(C)2015 Elsevier B.V.版权所有。
Background and Aim: The aim of this study was to investigate the association between short sleep duration and cardiovascular disease (CVD) risk factors including hypertension, diabetes, obesity and lipid profile among various ethnic groups (South Asian Surinamese, African Surinamese, Ghanaians, Turks, Moroccans and the Dutch) living in the Netherlands. The contribution of social economic status (SES) and lifestyle factors were also examined to this association.Method: A total of 12,805 participants (aged 18-70 years) from the multi-ethnic Healthy Life in an Urban Setting (HELIUS) cohort. Short sleep duration was defined as < 7 h/night. The association between short sleep and CVD risk factors, along with the contribution of SES and lifestyle factors, was assessed using prevalence ratios (PRs).Results: Short sleep was significantly associated with obesity in four out of six ethnic groups, with the socio-demographic-adjusted PR of 1.45 (95% CI, 1.07-1.95) in the Dutch, 1.21 (1.01-1.44) in South Asian Surinamese, 1.25 (1.09-1.43) in African Surinamese and 1.16 (1.04-1.29) in Turks. Short sleep was significantly associated with diabetes in African Surinamese (1.45, 1.14-1.84), Turks (1.59, 1.26-2.02) and Moroccans (1.29, 1.02-1.63). By contrast, the associations between other cardiovascular risk factors and short sleep were not significant in most ethnic groups, with the exception of the association with hypertension in the Dutch and Turks, and dyslipidaemia in South Asian Surinamese (reduced high-density lipoprotein cholesterol and triglyceride) and Moroccans (raised total cholesterol). SES and lifestyle factors contributed little to the observed associations.Conclusion: The findings indicate that short sleep is associated with obesity and diabetes in most ethnic groups. The associations for other risk factors vary between ethnic groups. Further studies are warranted to establish the potential factors that might lead to the observed differences across populations. (C) 2015 Elsevier B.V. All rights reserved.