Late presentation of HIV infection: a consensus definition
Late presentation of HIV infection: a consensus definition
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DOI：
10.1111/j.1468-1293.2010.00857.x
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发表时间：
2011-01-01
期刊：
影响因子：
3
通讯作者：
de Wolf, F.
中科院分区：
文献类型：
--
作者：
Antinori, A.;Coenen, T.;de Wolf, F.
在整个欧洲，几乎三分之一的艾滋病毒感染者直到感染后期才进入卫生保健。在整个欧洲，监测以确定迟发性表现发生的程度仍然不足，并且由于缺乏迟发性表现的共同临床定义而进一步复杂化。这篇文章的目的是提出一个共识的定义晚呈现HIV infection.MethodsOver过去的一年中，两项倡议已经走向了一个统一的定义。在2009年春天，他们共同努力，以确定一个共同的定义是什么意思是一个'晚呈现' patient.ResultsTwo定义达成一致，如下。迟交：CD 4细胞计数低于350个/μ L或出现艾滋病定义事件的患者，无论CD 4细胞计数如何。晚期艾滋病毒疾病的表现：CD 4细胞计数低于200个细胞/mL或出现AIDS定义事件的患者，无论CD 4细胞计数如何。研究人员能够在报告与艾滋病毒感染后期表现有关的监测或研究数据时实施这一定义（单独或与他们自己的首选定义一起）。
ObjectivesAcross Europe, almost a third of individuals infected with HIV do not enter health care until late in the course of their infection. Surveillance to identify the extent to which late presentation occurs remains inadequate across Europe and is further complicated by the lack of a common clinical definition of late presentation. The objective of this article is to present a consensus definition of late presentation of HIV infection.MethodsOver the past year, two initiatives have moved towards a harmonized definition. In spring 2009, they joined efforts to identify a common definition of what is meant by a 'late-presenting' patient.ResultsTwo definitions were agreed upon, as follows. Late presentation: persons presenting for care with a CD4 count below 350 cells/mu L or presenting with an AIDS-defining event, regardless of the CD4 cell count. Presentation with advanced HIV disease: persons presenting for care with a CD4 count below 200 cells/mL or presenting with an AIDS-defining event, regardless of the CD4 cell count.ConclusionThe European Late Presenter Consensus working group believe it would be beneficial if all national health agencies, institutions, and researchers were able to implement this definition ( either on its own or alongside their own preferred definition) when reporting surveillance or research data relating to late presentation of HIV infection.