SELECTIVE TRAFFICKING OF KNOTTED1 HOMEODOMAIN PROTEIN AND ITS MESSENGER-RNA THROUGH PLASMODESMATA
SELECTIVE TRAFFICKING OF KNOTTED1 HOMEODOMAIN PROTEIN AND ITS MESSENGER-RNA THROUGH PLASMODESMATA
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DOI：
10.1126/science.270.5244.1980
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发表时间：
1995-12-22
期刊：
影响因子：
56.9
通讯作者：
HAKE, S
中科院分区：
文献类型：
--
作者：
LUCAS, WJ;BOUCHEPILLON, S;HAKE, S
胞间连丝是植物细胞间的细胞器，在相邻细胞之间建立细胞质连续性。显微注射研究表明，胞间连丝促进植物编码的转录因子KNOTTED1（KN 1）的细胞到细胞的运输。KN 1还可以介导kn1正义RNA的选择性胞间连丝运输。植物发育的新图景表明，细胞命运至少部分取决于对细胞位置和谱系作出反应的超细胞控制。使必要的细胞间通讯的机制之一似乎涉及信息分子（蛋白质和RNA）通过胞间连丝的转移。
Plasmodesmata are intercellular organelles in plants that establish cytoplasmic continuity between neighboring cells. Microinjection studies showed that plasmodesmata facilitate the cell-to-cell transport of a plant-encoded transcription factor, KNOTTED1 (KN1). KN1 can also mediate the selective plasmodesmal trafficking of kn1 sense RNA. The emerging picture of plant development suggests that cell fate is determined at least in part by supracellular controls responding to cellular position as well as lineage. One of the mechanisms that enables the necessary intercellular communication appears to involve transfer of informational molecules (proteins and RNA) through plasmodesmata.