Dose distributions in dynamic stereotactic radiosurgery.
Dose distributions in dynamic stereotactic radiosurgery.
复制标题
动态立体定向放射外科的剂量分布。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
C. Pla
中科院分区：
文献类型：
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作者：
Bruce Pike;Ervin B. Podgorsak;Terence M. Peters;C. Pla
本文介绍了一种用10 MV等中心直线加速器进行动态立体定向放射外科治疗时剂量分布计算的治疗计划技术。动态放射外科的治疗计划是一个三维问题，因为在治疗过程中机架和治疗床同时旋转，机架从30度旋转到330度，治疗床从75度旋转到-75度。从计算机断层扫描或磁共振扫描系列中获得患者表面和解剖信息，并在治疗期间使用立体定向框架进行目标定位、治疗设置和患者固定。剂量计算算法以增量方式遵循机架和治疗床旋转，并依赖于测量的固定射束中心轴深度百分比剂量和剂量分布，以计算在三个正交平面（横向、矢状或冠状）之一上定义的点矩阵上的归一化组织最大比分布。详细讨论了剂量计算算法，并将单平面和动态放射外科的剂量分布计算结果与实测数据进行了比较。
A treatment planning technique for calculation of dose distributions in dynamic stereotactic "radiosurgery" with a 10-MV isocentrically mounted linear accelerator is presented. The treatment planning for dynamic radiosurgery is a three-dimensional problem, since during treatment both the gantry and the couch rotate simultaneously, the gantry from 30 degrees to 330 degrees and the couch from 75 degrees to - 75 degrees. The patient surface and anatomical information is obtained from a family of computed tomography or magnetic resonance scans, and a stereotactic frame is used for target localization, treatment setup, and patient immobilization during the treatment. The dose calculational algorithm follows the gantry and couch rotation in an incremental fashion, and relies on measured stationary beam central axis percentage depth doses and dose profiles to calculate the normalized tissue-maximum-ratio distributions over a matrix of points defined on one of three orthogonal planes (transverse, sagittal, or coronal). The dose calculation algorithm is discussed in detail and calculated dose distributions for single plane and dynamic radiosurgery compared with measured data.