Echoscintigraphy: A new imaging modality for the reduction of color blooming and acoustic shadowing in contrast sonography
Echoscintigraphy: A new imaging modality for the reduction of color blooming and acoustic shadowing in contrast sonography
复制标题
DOI：
10.1016/s0301-5629(03)00890-1
复制
发表时间：
2003-07-01
影响因子：
2.9
通讯作者：
Tiemann, K
中科院分区：
文献类型：
--
作者：
Schlosser, T;Pohl, C;Tiemann, K
本研究的目的是开发和评价一种新的成像方式（回声描记术），以减少彩色晕和声学阴影的造影超声。在将不同量（700至40，000个气泡/mL）的回波造影剂SH-U 563 A注入流动体模中后，在间歇谐波功率多普勒成像（H-PDI）模式下对人造血管进行声辐照。接收增益从50%到75%变化。使用新的求和算法（回波描记术）和H-PDI信号的传统单帧分析（S-FA）评估管的横截面积（CSA）。超声心动图是基于记录和汇总在超声（US）诱导的微泡破坏过程中发出的低强度信号。在低对比度浓度下应用求和算法，可以在中高增益设置下自动计算CSA。使用S-FA方法，血管直径和CSA的评估是增益依赖性的，仅允许在60%至65%增益范围内进行正确测量。在高接收增益和高对比浓度下，S-FA导致CSA的高估高达35.5%。超声造影术允许在低造影剂浓度下在宽范围的增益设置下正确显示造影剂填充的血管，其中S-FA不能充分显示回波对比度。因此，回波描记术最大限度地减少了由颜色模糊和声学阴影引起的伪影。（电子邮件：托马斯. uni-essen.de）（C）2003年世界医学生物学超声联合会。
The purpose of this study was to develop and evaluate a new imaging modality (echoscintigraphy) to reduce color blooming and acoustic shadowing in contrast sonography. After injection of various amounts (700 to 40,000 bubbles/mL) of the echo contrast agent SH-U 563A into a flow phantom, artificial vessels were insonated in the intermittent harmonic-power Doppler imaging (H-PDI) mode. The receive gain was varied from 50% to 75%. The cross-sectional area (CSA) of the tube was assessed using a new summation algorithm (echoscintigraphy) and a conventional single-frame analysis (S-FA) of the H-PDI-signals. Echoscintigraphy is based on the recording and summation of low-intensity signals that are emitted during the ultrasound (US)-induced destruction of microbubbles. Application of the summation algorithm at low-contrast concentration allowed a gain-independent automatic calculation of the CSA at medium and high gain settings. Using the S-FA method, the assessment of the vessel diameter and the CSA was gain-dependent and allowed correct measurements only from 60% to 65% gain. At a high receive-gain and high contrast concentration, S-FA resulted in an overestimation of the CSA up to 35.5%. Echoscintigraphy allows correct display of contrast-filled vessels over a wide range of gain settings at low contrast concentrations, where S-FA does not adequately display echo contrast. Thus, echoscintigraphy minimizes artefacts resulting from color blooming and acoustic shadowing. (E-mail: thomas.schlosser@uni-essen.de) (C) 2003 World Federation for Ultrasound in Medicine Biology.