Accelerating protons to therapeutic energies with ultraintense, ultraclean, and ultrashort laser pulses.
Accelerating protons to therapeutic energies with ultraintense, ultraclean, and ultrashort laser pulses.
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DOI：
10.1118/1.2900112
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发表时间：
2008-05
期刊：
影响因子：
3.8
通讯作者：
S. Bulanov;A. Brantov;V. Bychenkov;V. Chvykov;G. Kalinchenko;T. Matsuoka;P. Rousseau;S. Reed;V. Yanovsky;K. Krushelnick;D. Litzenberg;A. Maksimchuk
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文献类型：
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作者：
S. Bulanov;A. Brantov;V. Bychenkov;V. Chvykov;G. Kalinchenko;T. Matsuoka;P. Rousseau;S. Reed;V. Yanovsky;K. Krushelnick;D. Litzenberg;A. Maksimchuk
本文讨论了强激光脉冲在强子治疗中对质子的加速作用。随着密歇根大学的Hercules激光器将激光强度对比度提高到10（-1），可以在高达10（22）W/cm 2的强度下实现激光-固体相互作用，这允许从亚微米箔中有效地实现激光驱动离子加速。在预期的实验条件下，对Hercules激光脉冲能量为3 ~ 15 J，半高宽为30 fs，聚焦光斑尺寸为0.8 μ m的定向库仑爆炸质子加速过程进行了粒子模拟。在这种情况下，重离子主要在激光脉冲传播的方向上扩展，增强了加速轻离子的纵向电荷分离电场。已发现的最大质子能量的依赖性上的箔的厚度和激光脉冲特性已与目标的厚度相匹配，以确保最有效的加速。此外，质子光谱在高能量下显示出峰值结构，这是放射治疗所需的。二维PIC模拟表明，150-500 TW的激光脉冲能够将质子加速到100-220 MeV的能量。
Proton acceleration by high-intensity laser pulses from ultrathin foils for hadron therapy is discussed. With the improvement of the laser intensity contrast ratio to 10(-1) achieved on the Hercules laser at the University of Michigan, it became possible to attain laser-solid interactions at intensities up to 10(22) W/cm2 that allows an efficient regime of laser-driven ion acceleration from submicron foils. Particle-in-cell (PIC) computer simulations of proton acceleration in the directed Coulomb explosion regime from ultrathin double-layer (heavy ions/light ions) foils of different thicknesses were performed under the anticipated experimental conditions for the Hercules laser with pulse energies from 3 to 15 J, pulse duration of 30 fs at full width half maximum (FWHM), focused to a spot size of 0.8 microm (FWHM). In this regime heavy ions expand predominantly in the direction of laser pulse propagation enhancing the longitudinal charge separation electric field that accelerates light ions. The dependence of the maximum proton energy on the foil thickness has been found and the laser pulse characteristics have been matched with the thickness of the target to ensure the most efficient acceleration. Moreover, the proton spectrum demonstrates a peaked structure at high energies, which is required for radiation therapy. Two-dimensional PIC simulations show that a 150-500 TW laser pulse is able to accelerate protons up to 100-220 MeV energies.