Pleiotropic function of Toll-like receptors
Pleiotropic function of Toll-like receptors
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DOI：
10.1016/j.micinf.2004.08.019
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发表时间：
2004-12-01
影响因子：
5.8
通讯作者：
Akira, S
中科院分区：
文献类型：
--
作者：
Kaisho, T;Akira, S
A group of type I transmembrane proteins, Toll-like receptors (TLRs) discriminate various microorganism-associated molecular structures that can function as immune adjuvants. Each TLR signaling has an overlapping but distinct function, which largely depends on intracellular adaptor molecules. Clarifying the functions and signaling of TLRs should provide us with critical information for manipulating the host defense mechanism. (C) 2004 Elsevier SAS. All rights reserved.
