Synovial fluid cytokines and proteinases as markers of temporomandibular joint disease
Synovial fluid cytokines and proteinases as markers of temporomandibular joint disease
复制标题
DOI：
10.1016/s0278-2391(98)90868-0
复制
发表时间：
1998-02-01
影响因子：
1.9
通讯作者：
Murakami, KI
中科院分区：
文献类型：
--
作者：
Kubota, E;Kubota, T;Murakami, KI
目的：在这篇文章中，生化标志物在滑液（SF）检测关节内炎症和早期软骨退化的颞下颌关节（TMJ）diseases.Patients和方法：SF是从25个TMJ的22例内紊乱（ID）或骨关节炎（TMJ-GA），15个无症状TMJ在11名正常志愿者，和10个骨关节炎膝关节（KNEE-GA）。采用酶联免疫吸附法（ELISA）测定关节液中细胞因子水平，采用酶谱法测定关节液中蛋白酶活性。
Purpose: In this article, biochemical markers in the synovial fluid (SF) for detecting intraarticular inflammation and early cartilage degradation of the temporomandibular joint (TMJ) disease were examined.Patients and Methods: SF was obtained from 25 TMJs in 22 patients with internal derangement (ID) or osteoarthritis (TMJ-GA), 15 asymptomatic TMJs in 11 normal volunteers, and 10 osteoarthritic knee joints (KNEE-GA). Cytokine levels were measured by enzyme-linked immunosorbent assay (ELISA), and the proteinase activities were detected by enzymography.Results: SF from TMJs with ID and OA showed higher (P