Long-term changes in bone metabolism, bone mineral density, quantitative ultrasound parameters, and fracture incidence after spinal cord injury:: a cross-sectional observational study in 100 paraplegic men
Long-term changes in bone metabolism, bone mineral density, quantitative ultrasound parameters, and fracture incidence after spinal cord injury:: a cross-sectional observational study in 100 paraplegic men
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DOI：
10.1007/s00198-003-1529-6
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发表时间：
2004-03-01
影响因子：
4
通讯作者：
Lippuner, K
中科院分区：
文献类型：
--
作者：
Zehnder, Y;Lüthi, M;Lippuner, K
为了研究脊髓损伤（SCI）后脱矿物质和骨折发生率的时间过程，对100名运动功能完全丧失的截瘫男性进行了一项横断面研究，研究对象为创伤性SCI后3个月至30年。使用患者档案和X线片评估和验证骨折史。采用DXA测量腰椎（LS）、股骨颈（FN）、前臂远端（超远端部分=UDR，1/3远端部分=1/3R）、胫骨远端骨干（TDIA）和胫骨远端骨骺（TEPI）的BMD。使用QUS测量跟骨刚度（QUI.CALC）、胫骨声速（SOS.TIB）和近端指骨振幅依赖性SOS（adSOS.PHAL）。将BMD和定量超声（QUS）的Z评分与损伤后时间作图，并在根据损伤后时间（20年（p
To study the time course of demineralization and fracture incidence after spinal cord injury (SCI), 100 paraplegic men with complete motor loss were investigated in a cross-sectional study 3 months to 30 years after their traumatic SCI. Fracture history was assessed and verified using patients' files and X-rays. BMD of the lumbar spine (LS), femoral neck (FN), distal forearm (ultradistal part=UDR, 1/3 distal part=1/3R), distal tibial diaphysis (TDIA), and distal tibial epiphysis (TEPI) was measured using DXA. Stiffness of the calcaneus (QUI.CALC), speed of sound of the tibia (SOS.TIB), and amplitude-dependent SOS across the proximal phalanges (adSOS.PHAL) were measured using QUS. Z-Scores of BMD and quantitative ultrasound (QUS) were plotted against time-since-injury and compared among four groups of paraplegics stratified according to time-since-injury (20 years (p