Diffusion-weighted imaging reflects variable cellularity and stromal density present in breast fibroadenomas.

Diffusion-weighted imaging reflects variable cellularity and stromal density present in breast fibroadenomas.
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DOI:
10.1016/j.clinimag.2016.06.002
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发表时间:
2016-09
期刊:
影响因子:
2.1
通讯作者:
Partridge SC
Partridge SC
中科院分区:
医学4区
文献类型:
--
作者:
Parsian S;Giannakopoulos NV;Rahbar H;Rendi MH;Chai X;Partridge SC

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To determine the underlying histopathologic features influencing apparent diffusion coefficient (ADC) values of breast fibroadenomas. Biopsy proven fibroadenomas (n=26) initially identified as suspicious on breast MRI were retrospectively evaluated. Histopathological assessments of lesion cellularity and stromal type were compared with ADC measures on diffusion-weighted MRI. Presence of epithelial hyperplasia (increased cellularity) and dense collagenous stroma were both significantly associated with lower lesion ADC values (p=0.02 and 0.004, respectively. Variations in epithelial cellularity and stromal type influence breast lesion ADC values and may explain the wide range of ADC measures observed in benign fibroadenomas.
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