Impact of robotics on the outcome of elderly patients with endometrial cancer
Impact of robotics on the outcome of elderly patients with endometrial cancer
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DOI：
10.1016/j.ygyno.2014.03.572
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发表时间：
2014-06-01
影响因子：
4.7
通讯作者：
Gotlieb, Walter H.
中科院分区：
文献类型：
--
作者：
Lavoue, Vincent;Zeng, Xing;Gotlieb, Walter H.
目标。目的：探讨机器人技术对老年子宫内膜癌患者临床预后的影响。163例连续接受分期的高龄（>= 70岁）子宫内膜癌患者采用传统开放手术与机器人手术的围手术期发病率和无病间隔的评价与比较所有>= 70岁的连续接受机器人手术的子宫内膜癌患者（n = 113）与2007年12月引入机器人程序之前>= 70岁的所有连续患者（n = 50）进行比较。两个时代的基线患者特征相似。接受机器人手术的患者平均手术时间更长（244分钟比217分钟，p = 0.009），但轻微不良事件较少（17%比60%，p < 0.001）。机器人队列的估计平均失血量更少（75 vs 334 ml, p < 0.0001），平均住院时间更短（3 vs 6天，p < 0.0001）。在平均2年随访期间，两组无病生存率无差异（p = 0.61）。从开放手术过渡到机器人技术治疗老年子宫内膜癌有显著的好处，包括更低的轻微并发症发生率，更少的手术出血量和更短的住院时间，而不影响2年无病生存期。(C) 2014爱思唯尔公司版权所有。
Objective. To evaluate the impact of introducing a robotics program on clinical outcome of elderly patients with endometrial cancer.Methods. Evaluation and comparison of pen-operative morbidity and disease-free interval in 163 consecutive elderly patients (>= 70 years) with endometrial cancer undergoing staging procedure with traditional open surgery compared to robotic surgery.Results. All consecutive patients >= 70 years of age with endometrial cancer who underwent robotic surgery (n = 113) were compared with all consecutive patients >= 70 years of age (n = 50) before the introduction of a robotic program in December 2007. Baseline patient characteristics were similar in both eras. Patients undergoing robotic surgery had longer mean operating times (244 compared with 217 minutes, p = 0.009) but fewer minor adverse events (17% compared with 60%, p < 0.001). The robotics cohort had less estimated mean blood loss (75 vs 334 ml, p < 0.0001) and shorter mean hospital stay (3 vs 6 days, p < 0.0001). There was no difference in disease-free survival (p = 0.61) during the mean follow-up time of 2 years.Conclusion. Transitioning from open surgery to a robotics program for the treatment of endometrial cancer in the elderly has significant benefits, including lower minor complication rate, less operative blood loss and shorter hospitalization without compromising 2-year disease-free survival. (C) 2014 Elsevier Inc. All rights reserved.