Clinical significance of ascites in epithelial ovarian cancer
Clinical significance of ascites in epithelial ovarian cancer
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DOI：
10.4149/neo_2013_071
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发表时间：
2013-01-01
期刊：
影响因子：
3
通讯作者：
Liu, J. H.
中科院分区：
文献类型：
--
作者：
Huang, H.;Li, Y. J.;Liu, J. H.
腹水在上皮性卵巢癌（EOC）转移扩散中的预后意义尚不清楚。本研究旨在探讨临床病理因素与腹水发生的关系及其预后意义。333例原发性EOC患者适合纳入研究。我们分析了包括转移程度在内的临床病理因素与腹水体积的相关性。采用Kaplan-Meier法和多变量Cox回归分析评估腹水的预后意义。平均腹水容量为1800 ml， FIGO期晚期患者出现腹水的患者较多。当转移性疾病出现在三个以上的区域时，腹水的体积显著增加(p
The prognostic significance of ascites in the dissemination of metastases in epithelial ovarian cancer (EOC) is unclear. Our study aimed to investigate the association between clinicopathological factors and the development of ascites, as well as its prognostic significance. Three hundred and thirty three patients with primary EOC were suitable for inclusion. We analyzed the correlation between clinicopathological factors, including the extent of metastases, and ascitic volume. The prognostic significance of ascites was assessed using the Kaplan-Meier method and multivariate Cox's regression analysis. The average ascitic volume was 1,800 ml. Significantly, more patients with advanced FIGO stage disease presented with ascites. The volume of ascites increased significantly when metastatic disease was present in more than three regions (p