Selective C-O Bond Reduction and Borylation of Aryl Ethers Catalyzed by a Rhodium-Aluminum Heterobimetallic Complex
Selective C-O Bond Reduction and Borylation of Aryl Ethers Catalyzed by a Rhodium-Aluminum Heterobimetallic Complex
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DOI：
10.1021/jacs.1c03038
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发表时间：
2021-04-22
影响因子：
15
通讯作者：
Nakao, Yoshiaki
中科院分区：
文献类型：
--
作者：
Seki, Rin;Hara, Naofumi;Nakao, Yoshiaki
我们报道了带有 X 型 PAlP 钳配体的铑络合物对 C-O 键的催化还原和硼基化。我们根据反应中间体的表征和氘标记实验揭示了反应机理。值得注意的是，这种新型催化系统表现出与传统镍基催化剂不同的空间位阻依赖性化学选择性，并提出了一种通过异双金属催化选择性活化 C-O 键的新策略。
We report the catalytic reduction of a C-O bond and the borylation by a rhodium complex bearing an X-type PAlP pincer ligand. We have revealed the reaction mechanism based on the characterization of the reaction intermediate and deuterium-labeling experiments. Notably, this novel catalytic system shows steric-hindrance-dependent chemoselectivity that is distinct from conventional Ni-based catalysts and suggests a new strategy for selective C-O bond activation by heterobimetallic catalysis.