Direct comparison of two methods to measure T1:: in vitro and in vivo values by echo-planar imaging and by segmented k-space imaging
Direct comparison of two methods to measure T1:: in vitro and in vivo values by echo-planar imaging and by segmented k-space imaging
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DOI：
10.1016/j.mri.2004.01.021
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发表时间：
2004-04-01
影响因子：
2.5
通讯作者：
Steen, RG
中科院分区：
文献类型：
--
作者：
Haselgrove, J;Hunte, M;Steen, RG
我们测试的假设，质子T-1是准确测量独立的物理固有的方法。我们使用了两种经过充分验证但完全不同的成像方法来测量体模和人体中的T-1;回波平面成像T-one测量（EPITOME）方法和分段k空间采集精确和准确的反演恢复（TurboPAIR）方法。两种方法之间的一致性通常非常好;模型中相关系数（r（2））的平方为0.9996。志愿者脑组织中的r（2）总体为0.79，如果排除皮质灰质和胼胝体，则为0.85。尽管如此，在体内和T-1测量方法之间观察到小但显著的差异对组织类型敏感，尽管测量结果可以进行比较。两种方法之间的主要区别在于，EPITOME在低分辨率下对15个切片成像需要97 s，而TurboPAIR在高分辨率下对一个切片成像需要240 s。(C)2004爱思唯尔公司All rights reserved.
We test a hypothesis that proton T-1 is accurately measured independent of the physics inherent to the method. We used two well-validated but quite different imaging methods to measure T-1 in phantoms and in humans; an echo-planar imaging T-one measurement (EPITOME) method, and a segmented k-space acquisition precise and accurate inversion recovery (TurboPAIR) method. Agreement between the methods was generally excellent; the square of the correlation coefficient (r(2)) in phantoms was 0.9996. The r(2) in brain tissue of volunteers was 0.79 overall, and 0.85 if cortical gray matter and corpus callosum were excluded. Nevertheless, small but significant differences were observed between methods in vivo and T-1 measurements were sensitive to tissue type, although measurements could be made comparable. The major difference between the methods is that EPITOME takes 97 s to image 15 slices at low resolution, while TurboPAIR takes 240 s to image one slice at high resolution. (C) 2004 Elsevier Inc. All rights reserved.