[The respiratory facilitating effects by electrical and chemical stimulation of central nucleus amygdala].
[The respiratory facilitating effects by electrical and chemical stimulation of central nucleus amygdala].
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[电和化学刺激杏仁核中央核的呼吸促进作用]。
DOI：
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发表时间：
1992
期刊：
影响因子：
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通讯作者：
L. Liu
中科院分区：
文献类型：
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作者：
L. Nie;L. Liu
实验在50只乌拉坦麻醉（1 g/kg）、切断迷走神经和自主呼吸的雌雄家兔上进行。观察ACE电刺激和化学刺激的呼吸反应。结果如下：1.长串电刺激血管紧张素转换酶可产生明显的呼吸促进效应：吸气时间延长，呼吸频率和深度增加。2.在吸气中期和呼气中期短阵电刺激ACE分别引起吸气相延长和呼气关断（EO-S）效应。3. ACE内微量注射谷氨酰胺（MSG）（1 mol/L，1 μ l），产生与电刺激相似的呼吸效应。4.对照实验对呼吸没有显著影响。结果表明，ACE神经元的激活引起呼吸易化。提示ACE区可能在促进基础呼吸节律中起重要作用。
Experiments were performed on fifty urethan anesthetized (1 g/kg) rabbits of both sexes, vagotomized and spontaneously breathing. The respiratory responses to electrical and chemical stimulation of ACE were observed. The results were as follows: 1. Long train electrical stimulation of ACE caused significant respiratory facilitating effects: inspiratory prolongation and increase of respiratory rate and depth. 2. Short brust of electrical stimulation administered in ACE during the mid inspiratory and expiratory phases elicited the prolongation of inspiratory phase and the expiratory off-switch (EO-S) effect, respectively. 3. Microinjection of monosodium L-glutamate (MSG) (1 mol/L, 1 microliter) into ACE produced the similar respiratory effects as that of electrical stimulation. 4. Control experiments had no significant effect on respiration. The results showed that the activation of neurons in ACE caused facilitation of respiration. It is suggested that ACE region may take an important part in facilitating the basic respiratory rhythm.