Emotional brain states carry over and enhance future memory formation
Emotional brain states carry over and enhance future memory formation
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DOI：
10.1038/nn.4468
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发表时间：
2017-02-01
影响因子：
25
通讯作者：
Davachi, Lila
中科院分区：
文献类型：
--
作者：
Tambini, Arielle;Rimmele, Ulrike;Davachi, Lila
情绪唤醒可以对情绪体验产生持久、生动的记忆，但人们对情绪是否可以前瞻性地增强对暂时遥远信息的记忆形成知之甚少。可能支持预期记忆增强的一种机制是影响后续中性体验的情绪大脑状态的延续。在这里，我们发现，与情绪之前和中性刺激暴露之后的研究相比，人类受试者在暴露于情绪唤起的刺激后 9-33 分钟遇到的中性刺激在延迟记忆测试中具有更高的回忆水平。此外，对与情绪相关的大脑活动的多种测量显示，在随后的中性刺激编码期间有恢复的证据。在随后的中性编码过程中，缓慢的神经波动（低频连接）和预测情绪编码期间出现的逐次试验记忆形成的瞬时刺激诱发活动都得到了恢复。这些结果表明，情绪体验的神经测量可以持续一段时间，并且会影响新的、不相关的信息的编码和回忆方式。
Emotional arousal can produce lasting, vivid memories for emotional experiences, but little is known about whether emotion can prospectively enhance memory formation for temporally distant information. One mechanism that may support prospective memory enhancements is the carry-over of emotional brain states that influence subsequent neutral experiences. Here we found that neutral stimuli encountered by human subjects 9-33 min after exposure to emotionally arousing stimuli had greater levels of recollection during delayed memory testing compared to those studied before emotional and after neutral stimulus exposure. Moreover, multiple measures of emotion-related brain activity showed evidence of reinstatement during subsequent periods of neutral stimulus encoding. Both slow neural fluctuations (low-frequency connectivity) and transient, stimulus-evoked activity predictive of trial-by-trial memory formation present during emotional encoding were reinstated during subsequent neutral encoding. These results indicate that neural measures of an emotional experience can persist in time and bias how new, unrelated information is encoded and recollected.