COMORBIDITY IN HOARDING DISORDER

COMORBIDITY IN HOARDING DISORDER
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DOI:
10.1002/da.20861
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发表时间:
2011-10-01
影响因子:
7.4
通讯作者:
Tolin, David F.
Tolin, David F.
中科院分区:
医学1区
文献类型:
--
作者:
Frost, Randy O.;Steketee, Gail;Tolin, David F.

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背景:目前正在考虑将囤积症 (HD) 作为一种独特的疾病纳入 DSM-5 (1)。很少有研究考察囤积症患者的共病模式,以及那些存在严重方法缺陷的患者,包括从已诊断为强迫症 (OCD) 的人群中进行研究,使用过时的囤积症定义,以及依赖对囤积症的不充分评估。本研究是第一项针对符合最近提出的囤积症标准 (1) 并依赖于经过验证的评估程序的人群样本的合并症的大规模研究。方法:我们将大型 HD 样本 (n=217) 中的精神共病与 96 名符合强迫症标准但无 HD 的参与者进行了比较。结果:重度抑郁症 (MDD) 以及与获取相关的冲动控制障碍(强迫性购买、盗窃癖和获取免费物品)的合并症率很高。不到 20% 的 HD 参与者符合强迫症标准,并且男性 HD 中强迫症的发生率高于女性。 HD 参与者中 MDD 和习得相关冲动控制障碍的发生率高于 OCD 参与者。没有特定的焦虑障碍在 HD 中更常见,但 HD 男性中社交恐惧症比 OCD 男性中更常见。 28% 的 HD 参与者被诊断为注意力不集中 ADHD,并且明显高于 OCD 参与者 (3%)。结论:这些发现为开展囤积障碍的研究和治疗奠定了重要的基础。抑郁与焦虑 28: 876-884, 2011。(C) 2011 Wiley-Liss, Inc.
Background: Hoarding Disorder (HD) is currently under consideration for inclusion as a distinct disorder in DSM-5 (1). Few studies have examined comorbidity patterns in people who hoard, and the ones that have suffer from serious methodological shortcomings including drawing from populations already diagnosed with obsessive compulsive disorder (OCD), using outdated definitions of hoarding, and relying on inadequate assessments of hoarding. The present study is the first large-scale study of comorbidity in a sample of people meeting recently proposed criteria for hoarding disorder (1) and relying on validated assessment procedures. Methods: We compared psychiatric comorbidity in a large HD sample (n=217) to 96 participants meeting criteria for OCD without HD. Results: High comorbidity rates were observed for major depressive disorder (MDD) as well as acquisition-related impulse control disorders (compulsive buying, kleptomania, and acquiring free things). Fewer than 20% of HD participants met criteria for OCD, and the rate of OCD in HD was higher for men than women. Rates of MDD and acquisition-related impulse control disorders were higher among HD than OCD participants. No specific anxiety disorder was more frequent in HD, but social phobia was more frequent among men with HD than among men with OCD. Inattentive ADHD was diagnosed in 28% of HD participants and was significantly more frequent than among OCD participants (3%). Conclusions: These findings form important base rates for developing research and treatments for hoarding disorder. Depression and Anxiety 28: 876-884, 2011. (C) 2011 Wiley-Liss, Inc.