Imaging Tumor Metastases with Molecular Probes.
Imaging Tumor Metastases with Molecular Probes.
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DOI：
10.2174/1381612821666151027153943
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发表时间：
2015
影响因子：
3.1
通讯作者：
Ruirui Qiao;Ran Zhu;Mingyuan Gao
中科院分区：
文献类型：
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作者：
Ruirui Qiao;Ran Zhu;Mingyuan Gao
肿瘤转移是影响癌症患者长期生存率的重要预后因素。目前，没有成像模式或技术是理想的诊断转移。分子影像学为肿瘤转移的影像学检查提供了一个极好的工具。基于当前的医学成像工具，例如磁共振成像（MRI）、光学、单光子发射计算机断层扫描（SPECT）和正电子发射断层扫描（PET），已经开发了用于肿瘤转移的分子成像的各种技术和功能分子探针。本文就基于纳米探针的肿瘤转移分子成像的研究现状进行综述。
Tumor metastasis is an important prognostic factor regarding long-term survival rate of cancer patients. At present, no imaging modality or technique is ideal for diagnosis of metastases. Molecular imaging has provided a fantastic tool for tumor metastases imaging. Based on the current medical imaging tools such as magnetic resonance imaging (MRI), optical, single-photon emission computed tomography (SPECT), and positron emission tomography (PET), various techniques and functional molecular probes for molecular imaging of tumor metastases have been developed. In this review, we will summarize the current status of nanoprobe based molecular imaging metastases in cancer.