Idiopathic scoliosis and the vestibular system.
Idiopathic scoliosis and the vestibular system.
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DOI：
10.1007/s00586-014-3701-4
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发表时间：
2015-02
影响因子：
2.8
通讯作者：
Dorward, Ian G.
中科院分区：
文献类型：
--
作者：
Hawasli, Ammar H.;Hullar, Timothy E.;Dorward, Ian G.
尽管发病率很高，但特发性脊柱侧凸的病因尚不清楚。虽然最初的审查集中在遗传，生化，生物力学，营养和先天性原因，但越来越多的证据表明前庭系统的畸变可能在脊柱侧凸的病因中起作用。在这篇文章中，我们讨论了青少年特发性脊柱侧凸的可能机制，并回顾了目前支持前庭系统在青少年特发性脊柱侧凸中的作用的证据。使用PubMed （http://www.ncbi.nlm.nih.gov/pubmed）对英文文献进行了全面的检索。研究青少年特发性脊柱侧凸与前庭系统之间相互作用的研究文章被选择并评估纳入文献综述。18篇3-4级临床证据手稿支持AIS与前庭系统功能障碍之间的关联。这些研究包括来自人类生理和形态学研究的数据。临床数据得到动物模型研究的支持，表明前庭系统与AIS之间存在因果关系。临床数据和有限数量的动物模型研究表明，前庭系统在AIS中起着致病作用，尽管这种关联并未在所有研究中得到证实。
Despite its high prevalence, the etiology underlying idiopathic scoliosis remains unclear. Although initial scrutiny has focused on genetic, biochemical, biomechanical, nutritional and congenital causes, there is growing evidence that aberrations in the vestibular system may play a role in the etiology of scoliosis. In this article, we discuss putative mechanisms for adolescent idiopathic scoliosis and review the current evidence supporting a role for the vestibular system in adolescent idiopathic scoliosis. A comprehensive search of the English literature was performed using PubMed (http://www.ncbi.nlm.nih.gov/pubmed). Research articles studying interactions between adolescent idiopathic scoliosis and the vestibular system were selected and evaluated for inclusion in a literature review. Eighteen manuscripts of level 3-4 clinical evidence to support an association between AIS and dysfunction of the vestibular system. These studies include data from physiologic and morphologic studies in humans. Clinical data are supported by animal model studies to suggest a causative link between the vestibular system and AIS. Clinical data and a limited number of animal model studies suggest a causative role of the vestibular system in AIS, although this association has not been reproduced in all studies.
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影响因子：
2.4
作者：
Gruber, Allison H.;Busa, Michael A.;Hamill, Joseph
通讯作者：
Hamill, Joseph
影响因子：
3
作者：
Guo, Xia;Chau, W. W.;Cheng, Jack C. Y.
通讯作者：
Cheng, Jack C. Y.
影响因子：
3
作者：
Lion, Alexis;Haumont, Thierry;Perrin, Philippe P.
通讯作者：
Perrin, Philippe P.
DOI：
10.1097/00002517-199506000-00001
发表时间：
1995-06-01
期刊：
JOURNAL OF SPINAL DISORDERS
影响因子：
--
作者：
DEGUCHI, M;KAWAKAMI, N;IWATA, H
通讯作者：
IWATA, H
影响因子：
3
作者：
Kuo, Fang-Chuan;Hong, Chang-Zern;Tan, Shih-Hsin
通讯作者：
Tan, Shih-Hsin