Biological monitoring of organophosphate pesticides in preschool children in an agricultural community in Thailand

Biological monitoring of organophosphate pesticides in preschool children in an agricultural community in Thailand
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DOI:
10.1179/oeh.2006.12.2.134
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发表时间:
2006-04-01
影响因子:
--
通讯作者:
Robson, Mark G.
Robson, Mark G.
中科院分区:
医学4区
文献类型:
--
作者:
Petchuay, Chidhathai;Visuthismajarn, Parichart;Robson, Mark G.

文献摘要

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确定了泰国农业社区学龄前儿童和同一分区农场区域外的参考儿童的有机磷农药暴露情况。在第一天早晨的排尿样本中测量二烷基磷酸盐 (DAP) 代谢物的水平。在旱季(四月至五月),农场儿童排泄的所有 DAP 代谢物水平显着高于参考儿童(Mann-Whitney U 检验,p < 0.05;Wilcoxon 符号排序文本,p < 0.05)。在雨季(9 月至 10 月),两组的 DAP 代谢水平相似。参考儿童没有表现出与季节相关的显着差异。旱季喷洒农药可能是农场儿童接触有机磷酸盐的一个原因。
Organophosphate pesticide exposures of preschool children in a Thailand agricultural community and reference children living outside the farm area in the same subdistrict were determined. Levels of dialkylphosphate (DAP) metabolites were measured in first-morning-void urine samples. During the dry season (April-May), the farm children excreted significantly higher levels of all DAP metabolites than the reference children did (Mann-Whitney U test, p < 0.05; Wilcoxon signed-rank text, p < 0.05). During the wet season (September-October), DAP metabolite levels were similar in the two groups. Reference children showed no significant difference related to season. Pesticide spraying during the dry season is a likely cause of the farm children's organohosphate exposures.