Distribution across cortical areas of neurons projecting to the superior colliculus in New World Monkeys
Distribution across cortical areas of neurons projecting to the superior colliculus in New World Monkeys
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DOI：
10.1002/ar.a.20207
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发表时间：
2005-07-01
期刊：
影响因子：
--
通讯作者：
Kaas, JH
中科院分区：
文献类型：
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作者：
Collins, CE;Lyon, DC;Kaas, JH
令人惊讶的是，我们对灵长类动物新皮层不同区域向上级丘投射的比例知之甚少。为了获得这种投射模式的概述，我们在三只新大陆猴（Callithrix、Callicebus和Aotus）的上级丘中共注射了10次逆行示踪剂。由于皮质是扁平的，平行于表面切割，标记的皮质顶盖神经元可以准确地定位相对于建筑边界和表面特征。虽然病例和注射部位之间存在变异性，但汇总结果明确支持几个结论。1、3个清晰的视区，V1（18%）、V2（14%）和MT（11%），占标记细胞总数的近一半。第二，其他几个视觉区域（V3、DL、DM和FST）位于处理层次的早期，占总数的五分之一。三，下颞视觉区的腹侧流只提供了轻微的预测。第四，视野（FEF，FV，SEF区域的皮质和后顶叶皮质）包含不到10%的标记神经元。5、听觉区和躯体感觉区标记神经元较少。结果表明，皮质输入的上级丘主要来自早期的视觉区，而不是从多模态或视觉区。(c)2005 Wiley-Liss，Inc.
Surprisingly little is known about the proportions of projections of different areas and regions of neocortex to the superior colliculus in primates. To obtain an overview of such projection patterns, we placed a total of 10 injections of retrograde tracers in the superior colliculus of three New World monkeys (Callithrix, Callicebus, and Aotus). Because cortex was flattened and cut parallel to the surface, labeled corticotectal neurons could be accurately located relative to architectonic boundaries and surface features. While there was variability across cases and injection sites, the summed results clearly support several conclusions. One, three well-defined visual areas, V1 (18%), V2 (14%), and MT (11%), contributed nearly half of the total of labeled cells. Two, several other visual areas (V3, DL, DM, and FST) that are early in the processing hierarchy provided another fifth of the total. Three, inferior temporal visual areas of the ventral stream provided only minor projections. Four, visuomotor fields (FEF, FV, cortex in the region of SEF, and posterior parietal cortex) contained less than 10% of the labeled neurons. Five, few labeled neurons were in auditory or somatosensory areas. The results indicate that cortical inputs to the superior colliculus originate predominantly from early visual areas rather than from multimodal or visuomotor areas. (c) 2005 Wiley-Liss, Inc.