Quality of life outcomes in patients with breast cancer.
Quality of life outcomes in patients with breast cancer.
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DOI：
10.4081/oncol.2012.e2
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发表时间：
2012-03-05
期刊：
影响因子：
3.6
通讯作者：
Paraskevi T
中科院分区：
文献类型：
--
作者：
Paraskevi T
与健康相关的生活质量现在被认为是癌症临床试验的重要终点。研究表明，评估癌症患者的生活质量有助于改善治疗，甚至可以与医疗参数一起作为预后因素。本文根据之前的描述性研究结果对乳腺癌患者的生活质量结果进行了回顾。这是对 1987 年至 2008 年间出现在英语生物医学期刊上的出版物的文献的书目综述。搜索策略包括在已发表文章的标题中结合关键词“生活质量”和“乳腺癌”。主要研究结果以不同标题进行总结和介绍：i) 诊断时、ii) 治疗期间和 iii) 治疗完成后健康相关生活质量的评估。接受化疗的乳腺癌患者可能会出现一些副作用和症状，对他们的生活质量产生负面影响。辅助激素疗法也被发现对生活质量有类似的负面影响。研究发现，乳腺癌患者普遍存在心理困扰——焦虑和抑郁。症状——疼痛、疲劳和失眠是最常见的症状。有大量关于乳腺癌患者生活质量的文献。这些论文为改善乳腺癌护理做出了相当大的贡献。
Health-related quality of life is now considered an important endpoint in cancer clinical trials. It has been shown that assessing quality of life in cancer patients could contribute to improved treatment and could even serve as a prognostic factor along with medical parameters. This paper presents a review of quality of life outcomes in patients with breast cancer according to previous descriptive findings. This is a bibliographic review of the literature covering publications that appeared in English language biomedical journals between 1987 and 2008. The search strategy included a combination of the key words quality of life and breast cancer in the titles of published articles. The major findings are summarized and presented under different headings: evaluation of health-related quality of life i) at the time of diagnosis, ii) during treatment, and iii) after the completion of treatment. Breast cancer patients receiving chemotherapy might experience several side-effects and symptoms that have a negative effect on their quality of life. Also adjuvant hormonal therapies were found to have a similar negative impact on quality of life. Psychological distress-anxiety and depression were found to be common among breast cancer patients. Symptoms-pain, fatigue, and insomnia were among the most common symptoms reported. There was quite an extensive body of literature on quality of life in breast cancer patients. These papers have made a considerable contribution to improving breast cancer care.