Intraparotid facial nerve schwannoma: a 17-year, single-institution experience of diagnosis and management
Intraparotid facial nerve schwannoma: a 17-year, single-institution experience of diagnosis and management
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腮腺内面神经神经鞘瘤：17 年单机构诊断和治疗经验
DOI：
10.1080/00016489.2019.1574983
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发表时间：
2019-02
影响因子：
1.4
通讯作者：
Zhigang Cai
中科院分区：
文献类型：
--
作者：
Shijun Li;Xuguang Lu;Shang Xie;Zimeng Li;Xiaofeng Shan;Zhigang Cai
摘要背景：腮腺内面神经鞘瘤（IFNS）是一种罕见的肿瘤，术前诊断困难。目的：提高对干扰素综合征（IFNS）诊断的认识，并提出合理的治疗方案。材料与方法：回顾性分析我院IFNS患者的病历资料。入选标准为腮腺肿块手术（2000年1月至2016年12月），病理诊断为神经鞘瘤。结果：该研究包括42名合格的患者，他们从5977名腮腺肿瘤患者中接受了肿瘤切除术。肿块多呈质地坚硬（18/39）或质地中等（15/39），活动受限（21/39），其中3个肿块不可触及。他们的面神经功能结局为House-Brackmann I级（n = 14）、II级（n = 7）、III级（n = 11）、IV级（n = 5）、V级（n = 3）和VI级（n = 2）。根据所用的不同手术方法（p = .000）和肿瘤累及情况（p = .002），结果存在显著差异。结论和意义：腮腺内质地坚硬的肿瘤伴活动受限的肿块应提示神经鞘瘤的诊断。肿瘤累及主干常导致面神经预后不良。面神经的保留是必不可少的，剥离手术或囊内摘除术可能是首选的手术方法。
Abstract Background: Intraparotid facial nerve schwannoma (IFNS) is rare and its definite preoperative diagnosis is challenging. Objective: To improve available knowledge regarding the diagnosis of IFNS and to suggest an appropriate treatment plan. Material and methods: We retrospectively analyzed medical records of IFNS patients at our hospital. Inclusion criteria were surgery (from January 2000, to December 2016) for a parotid mass, pathologically diagnosed as a schwannoma. Results: The study included 42 eligible patients who had undergone tumor resection from 5977 parotid tumor patients. Mostly presented hard-textured (18/39) or medium-textured (15/39), with limited mobility (21/39) mass (three tumors were not palpable). Their facial nerve function outcomes were House–Brackmann Grade I (n = 14), Grade II (n = 7), Grade III (n = 11), Grade IV (n = 5), Grade V (n = 3), and Grade VI (n = 2). Significant differences were noted in results based on different surgical methods used (p = .000) and tumor involvement (p = .002). Conclusions and significance: A hard-textured tumor with limited mobility mass in the parotid gland should prompt the diagnosis of a schwannoma. Tumors involving main trunk usually lead to unsatisfactory facial nerve outcomes. Facial nerve preservation should always be essential, and stripping surgery or intracapsular enucleation could be the preferred surgical methods of choice.
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影响因子：
2.1
作者：
A. Kreeft;P. Schellekens;H. Leverstein
通讯作者：
A. Kreeft;P. Schellekens;H. Leverstein
影响因子：
4.5
作者：
J. Pang;A. Mahar;K. Shannon;J. Kench;Charles Chan;Ruta Gupta
通讯作者：
J. Pang;A. Mahar;K. Shannon;J. Kench;Charles Chan;Ruta Gupta
DOI：
10.1177/000348940111000912
发表时间：
2001-09
期刊：
Annals of Otology, Rhinology & Laryngology
影响因子：
--
作者：
Ching-Wen Chiang;Yih-Leong Chang;P. Lou
通讯作者：
Ching-Wen Chiang;Yih-Leong Chang;P. Lou
影响因子：
2.5
作者：
Dongdong Xiang;Liang Liu;Yefeng Li;J-Y Qiao
通讯作者：
Dongdong Xiang;Liang Liu;Yefeng Li;J-Y Qiao
DOI：
10.1016/j.joms.2016.02.002
发表时间：
2016-08
期刊：
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
影响因子：
--
作者：
Guo Zhi Zhang;T. Su;Jian Xu;Zhi-qiang Cheng
通讯作者：
Guo Zhi Zhang;T. Su;Jian Xu;Zhi-qiang Cheng