Convenient Synthesis of Benzo[4,5]thiazolo[2,3-c][1,2,4]triazoleswith 1 mol% CuCl22H2O as Catalyst in Water
Convenient Synthesis of Benzo[4,5]thiazolo[2,3-c][1,2,4]triazoleswith 1 mol% CuCl22H2O as Catalyst in Water
复制标题
方便%20%20of%20苯并[4,5]噻唑并[2,3-c][1,2,4]三唑与%201%20mol%%20CuCl22H2O%20as%20催化剂%20in%20水的合成
DOI：
10.1039/c4gc02156h
复制
发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Ming Li
中科院分区：
文献类型：
--
作者：
Li-Rong Wen;Shou-Lei Li;Jian Zhang;Ming Li
以邻溴芳基异硫氰酸酯和芳香酰肼为原料，通过分子间C-N键和分子内C-S键的串联形成，建立了一种简便高效的苯并[4,5]噻唑[2,3-c][1,2,4]三唑的合成方法。以1 mol% CuCl2·2H2O/1 mol% 1,10-菲罗啉为催化剂，水为溶剂，制备了一系列苯并[4,5]噻唑[2,3-c][1,2,4]三唑，总收率较高。
A convenient and efficient procedure for the synthesis of benzo[4,5]thiazolo [2,3-c][1,2,4]triazoles has been developed via a tandem intermolecular C–N bond and intramolecular C–S bond formation sequence from o-bromo-arylisothiocyanates and aroylhydrazides. A series of benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles were provided in excellent overall yields with 1 mol% CuCl2·2H2O/1 mol% 1,10-phenanthroline as the catalyst and water as the solvent.