Randomized psychosocial interventions for breast cancer: impact on life purpose.
Randomized psychosocial interventions for breast cancer: impact on life purpose.
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DOI：
10.1002/pon.3891
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发表时间：
2016-06
期刊：
影响因子：
3.6
通讯作者：
Scheier MF
中科院分区：
文献类型：
--
作者：
Mens MG;Helgeson VS;Lembersky BC;Baum A;Scheier MF
本研究试图确定教育和同伴支持干预对乳腺癌女性患者的影响的中介因素，并确定同伴支持干预的效果是否受到癌症严重程度的影响。参与者包括180名早期(I或II)乳腺癌患者和65名晚期(IV)乳腺癌患者。这项研究最初计划为2(早期、晚期)×3(教育干预、同伴支持干预、对照条件)设计；然而，由于招募缓慢，晚期癌症组的教育条件被放弃。参与者在被随机分组之前(时间1)完成幸福感测量，然后在小组会议结束后2周(时间2)和6个月后(时间3)再次完成幸福感测量。在至少参加过一次小组会议的参与者中，教育干预在时间2预测了更多的生活目标，并略微预测了更多的身体健康。同伴支持干预在时间2预测了更多的生活目标和较少的抑郁症状。癌症的严重程度并不能缓解这些影响。同伴支持干预对抑郁症状的影响受生活目的的影响。同伴支持干预对晚期和早期乳腺癌妇女的幸福感有积极的短期影响，这些影响部分地通过生活目标的改变来调节。教育干预对早期乳腺癌妇女的幸福感有积极的短期影响。
The present study sought to identify mediators underlying the effects of an education and a peer support intervention for women with breast cancer, and to determine if the efficacy of a peer support intervention is moderated by cancer severity. Participants included 180 patients with early stage (I or II) and 65 patients with late stage (IV) breast cancer. The study was originally planned as a 2 (early stage, late stage) X 3 (education intervention, peer support intervention, control condition) design; however, the education condition for the late stage cancer group was dropped, due to slow recruitment. Participants completed measures of well-being prior to being randomized (Time 1), then again 2 weeks after the group meetings ended (Time 2), and 6 months later (Time 3). Among participants who had attended at least one group meeting, the education intervention predicted more life purpose, and marginally predicted more perceived physical health at Time 2. The peer support intervention predicted more life purpose and less depressive symptoms at Time 2. Cancer severity did not moderate these effects. The effect of the peer support intervention on depressive symptoms was mediated by life purpose. None of the intervention effects were evident at Time 3. Peer support interventions have positive short-term effects on well-being, among women with late and early stage breast cancer, and these effects are partially mediated by changes in life purpose. Education interventions have positive short-term effects on well-being among women with early stage breast cancer.