Efferent inhibition in the cochlea related to hair-cell dc activity: study of postsynaptic activity of the crossed olivocochlear fibres in the cat.
Efferent inhibition in the cochlea related to hair-cell dc activity: study of postsynaptic activity of the crossed olivocochlear fibres in the cat.
复制标题
与毛细胞直流活性相关的耳蜗传出抑制：猫交叉橄榄耳蜗纤维突触后活性的研究。
DOI：
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发表时间：
1967
影响因子：
2.4
通讯作者：
J. Fex
中科院分区：
文献类型：
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作者：
J. Fex
用微电极记录28只猫交叉橄榄耳蜗纤维诱发的耳蜗内直流电位。从Corti器到中阶，直流电位从正变为负，并以4-10倍的倍数增大，达到−3 mV（相对于耳蜗外的参考电极）。结论是，直流电位代表突触后活动，由交叉的橄榄耳蜗纤维撞击外毛细胞产生，并且听觉神经纤维受到这种活动的突触前抑制。新的和以前的研究结果的行动的交叉olivoclear纤维进行了讨论，目前的概念，summating电位。离心和声诱发的dc活动相互作用的发现表明，毛细胞中的声音诱发的dc活动可能调节听觉神经纤维的活动。新的和以前的研究结果的非交叉橄榄耳蜗纤维进行了讨论。初步假设是亲…
Intracochlear dc potentials were evoked by stimulating the crossed olivocochlear fibres and were recorded with microelectrodes in 28 cats. From the organ of Corti to the scala media, the dc potentials changed from positive to negative and became larger by a factor of 4–10, reaching −3 mV relative to a reference electrode outside the cochlea. It is concluded that the dc potentials represented postsynaptic activity, generated by crossed olivocochlear fibres impinging on outer hair cells, and that auditory‐nerve fibres are presynaptically inhibited by such activity. New and previous findings on the action of the crossed olivocochlear fibres are discussed in relation to present concepts of summating potentials. The findings that centrifugally and acoustically evoked dc activity interact are taken to indicate that sound‐evoked dc activity in hair cells might regulate activity in auditory nerve fibres. New and previous findings on the uncrossed olivocochlear fibres are discussed. The tentative hypothesis is pro...