HLA class I antigen abnormalities and immune escape by malignant cells

HLA class I antigen abnormalities and immune escape by malignant cells
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DOI:
10.1006/scbi.2001.0404
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发表时间:
2002-02-01
影响因子:
14.5
通讯作者:
Ferrone, S
Ferrone, S
中科院分区:
医学1区
文献类型:
--
作者:
Seliger, B;Cabrera, T;Ferrone, S

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本文中使用的缩写:APM,抗原加工机制; β 2 m,β 2微球蛋白; bp,碱基对; CTL,细胞毒性T淋巴细胞; ER,内质网; HC,重链; HNSCC,头颈部鳞状细胞癌; IFN,干扰素; IL,白细胞介素; KIR,杀伤抑制受体; LMP,低分子量蛋白质;洛,杂合性缺失; mAb,单克隆抗体; MHC,主要组织相容性复合体; NK,自然杀伤细胞; PA,蛋白酶体激活剂; PCR,聚合酶链反应; RCC,肾细胞癌; SCLC,小细胞肺癌; TAA,肿瘤相关抗原; TAP,抗原加工相关转运蛋白; TCR,T细胞受体; TNF,肿瘤坏死因子; wt,野生型。
Abbreviations used in this paper: APM, antigen processing machinery; β2m,β2microglobulin; bp, base pair; CTL, cytotoxic T lymphocytes; ER, endoplasmic reticulum; HC, heavy chain; HNSCC, head and neck squamous cell carcinoma; IFN, interferon; IL, interleukin; KIR, killing inhibitory receptors; LMP, low molecular weight proteins; LOH, loss of heterozygosity; mAb, monoclonal antibody; MHC, major histocompatibility complex; NK, natural killer; PA, proteasome activator; PCR, polymerase chain reaction; RCC, renal cell carcinoma; SCLC, small cell-lung carcinoma; TAA, tumor-associated antigens; TAP, transporter associated with antigen processing; TCR, T cell receptor; TNF, tumor necrosis factor; wt, wild-type.