CHANGES IN THE NORMAL CORNEAL ENDOTHELIAL CELLULAR-PATTERN AS A FUNCTION OF AGE
CHANGES IN THE NORMAL CORNEAL ENDOTHELIAL CELLULAR-PATTERN AS A FUNCTION OF AGE
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DOI：
10.3109/02713688509017661
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发表时间：
1985-01-01
影响因子：
2
通讯作者：
EDELHAUSER, HF
中科院分区：
文献类型：
--
作者：
YEE, RW;MATSUDA, M;EDELHAUSER, HF
通过镜面显微镜和计算机辅助形态测量法定量观察人体内皮细胞的形态学变化，建立各种形态学参数的正常基线。细胞多聚性和细胞多形性随年龄增长而增加，正常基线参数详细。正常角膜的各项形态学参数在左右眼、中央内皮细胞和周围内皮细胞之间均无显著差异。这些正常的形态学基线可以用来检测早期角膜内皮病理和/或细胞密度测量无法检测到的细胞损失。
Human endothelial morphologic changes were quantitated by specular microscopy and computer-assisted morphometry to establish normal baselines of various morphologic parameters. Cellular polymegethism and cellular pleomorphism increases with age, and normal baseline parameters are detailed. No significant difference in any morphologic parameters between the right and left eye and between central and peripheral endothelium was detected in the normal corneas examined. These normal morphologic baselines can possibly be utilized to detect early corneal endothelial pathology and/or cell loss nondetectable by cell density measurement.