Nonlinear electrophoresis of nonspherical particles in a rectangular microchannel
Nonlinear electrophoresis of nonspherical particles in a rectangular microchannel
复制标题
矩形微通道中非球形颗粒的非线性电泳
DOI：
10.1002/elps.202300188
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发表时间：
2023
期刊：
影响因子：
2.9
通讯作者：
Xuan, Xiangchun
中科院分区：
文献类型：
--
作者：
Bentor, Joseph;Xuan, Xiangchun
与线性电泳相比，非线性电泳在微流控颗粒处理方面具有更广阔的应用前景。为这种现象建立的现有理论完全基于球形粒子模型，其中一些已经得到了实验验证。然而，对于颗粒形状是否以及如何影响非线性电泳行为还没有明确的认识。本文对矩形微通道中刚性花生形和梨形颗粒的非线性电泳速度进行了实验研究，并将其与具有相似直径和表面电荷的刚性球形颗粒进行了长细比的比较。我们观察到，当颗粒长细度从花生形到梨形和球形颗粒增加时，非线性电泳迁移率降低，而非线性电场指数增加。而非球形粒子的非线性指标值仍在球形粒子的理论预测范围内。我们还观察到，在较低浓度的缓冲溶液中，无论颗粒形状如何，非线性电泳行为都有所增强。
Nonlinear electrophoresis offers advantageous prospects in microfluidic manipulation of particles over linear electrophoresis. Existing theories established for this phenomenon are entirely based on spherical particle models, some of which have been experimentally verified. However, there is no knowledge on if and how the particle shape may affect the nonlinear electrophoretic behavior. This work presents an experimental study of the nonlinear electrophoretic velocities of rigid peanut‐ and pear‐shaped particles in a rectangular microchannel, which are compared with rigid spherical particles of similar diameter and surface charge in terms of the particle slenderness. We observe a decrease in the nonlinear electrophoretic mobility, whereas an increase in the nonlinear index of electric field when the particle slenderness increases from the peanut‐ to pear‐shaped and spherical particles. The values of the nonlinear index for the nonspherical particles are, however, still within the theoretically predicted range for spherical particles. We also observe an enhanced nonlinear electrophoretic behavior in a lower concentration buffer solution regardless of the particle shape.