The BRCA Self-Concept Scale: a new instrument to measure self-concept in BRCA1/2 mutation carriers
The BRCA Self-Concept Scale: a new instrument to measure self-concept in BRCA1/2 mutation carriers
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DOI：
10.1002/pon.1498
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发表时间：
2009-11-01
期刊：
影响因子：
3.6
通讯作者：
Irwin, Ellen
中科院分区：
文献类型：
--
作者：
Esplen, Mary Jane;Stuckless, Noreen;Irwin, Ellen
BRCA 1/2基因检测具有心理社会影响，包括与个人健康，自我和身份感以及身体形象相关的观点。一个人的自我概念在维持身体和心理健康方面的中心地位已经得到了很好的认可;然而，迄今为止，探索与载体知识相关的自我概念改变的研究是有限的。目的：本研究的目的是开发和验证一个量表来测量BRCA 1/2突变阳性个体的自我概念。项目生成和细化以及第二阶段：量表选择和初步验证。在第一阶段，量表项目是通过对BRCA 1/2突变女性的个别访谈和焦点小组产生的，包括既往诊断为癌症或未诊断为癌症的女性。在第二阶段，根据几个标准选择项目，产生一个25个项目的规模，进行了可靠性分析和初步验证与115名妇女。第二个样本126名妇女进行进一步的验证和样本合并进行因素分析和最终的量表选择。结果：一个17个项目的自我概念量表出现了三个因素：耻辱，脆弱性和掌握证明了证据，具有良好的心理测量学性质的工具（总尺度α = 0.90）。结论：该量表与研究直接相关，有助于我们了解自我的特定方面，这些方面易受BRCA 1/2检测的影响，并在临床结果中发挥作用，以促进干预措施的制定和具体测试，并可用作成果衡量标准。遗传群体的特定测量工具将最终有助于这些群体的临床管理。版权所有（C）2009约翰威利父子有限公司
Genetic testing for BRCA1/2 has psychosocial impacts including those related to views of personal health, sense of self and identity and body image. The centrality of a person's self-concept in maintaining physical and psychosocial well-being has been well recognized; however, to date research exploring altered self-concept related to carrier knowledge is limited.Objective: The objective of the study was to develop and validate a scale to measure the self-concept among individuals testing positive for BRCA1/2 mutations.Methods: The study was conducted in two phases: phase 1: item generation and refinement and phase II: scale selection and initial validation. During phase 1, scale items were generated through individual interviews and focus groups of women with BRCA1/2 mutations, including women with or without a prior diagnosis of cancer. In phase II items were selected based on several criteria resulting in a 25-item scale, which underwent a reliability analyses and preliminary validation with 115 women. A second sample of 126 women was used to conduct further validation and samples were pooled to conduct factor analysis and the final scale selection.Results: A 17-item self-concept scale emerged having three factors: stigma, vulnerability and mastery demonstrating evidence for an instrument with promising psychometric properties (total scale alpha = 0.90).Conclusions: The scale has direct relevance for research in facilitating our understanding of the specific aspects of the self, which are vulnerable to BRCA1/2 testing and which play a role in clinical outcomes, to facilitate the development and specific testing of interventions and may be used as an outcome measure. Specific measurement tools for genetic populations will ultimately assist in the clinical management of these populations. Copyright (C) 2009 John Wiley & Sons, Ltd.