Detection of infectious haematopoietic necrosis virus in river water and demonstration of waterborne transmission
Detection of infectious haematopoietic necrosis virus in river water and demonstration of waterborne transmission
复制标题
河水中传染性造血坏死病毒的检测及水源传播示范
DOI：
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
C. K. Jenes
中科院分区：
文献类型：
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作者：
D. Mulcahy;R. Pascho;C. K. Jenes
。在一项关于水媒传染性造血坏死病毒在产卵红三文鱼(Oncorhynchus Nerka(Walbaum))传播疾病中的可能作用的研究中，在一侧水道高密度养殖的鱼的感染率和病毒滴度都高于邻近河流中的鱼。从未从河水中分离出病毒，但在侧水道的水中发现了32.5至1600个菌斑形成单位(Pf.u)/毫升的水平。未受感染的一岁红鲑鱼被放在侧水道的一个盒子里，发生了局部的IHN病毒鳃感染。直到在鳃中达到约105p.f.u/g的阈值滴度，疾病才发展到内脏。鳃作为限制系统感染发展的屏障的有效性意味着，水传播的IHN病毒可能不会在产卵期间大幅增加红鲑鱼种群的感染率。
. In a study of the possible role of waterborne infectious haematopoietic necrosis virus in transmission of the disease among spawning sockeye salmon, Oncorhynchus nerka (Walbaum), both infection rates and virus titres were higher in fish held at high density in a side channel than in fish in the adjacent river. Virus was never isolated from river water, but was found in water from the side channel at levels ranging from 32.5 to 1600 plaque-forming units (p.f.u.)/ml. Uninfected yearling sockeye salmon held in a box in the side channel developed localized gill infections with IHN virus. The disease did not progress to the viscera until a threshold titre of about 105 p.f.u./g was reached in the gill. The effectiveness of the gill as a barrier limiting development of systemic infections means that waterborne IHN virus probably does not greatly increase the infection rate in a sockeye salmon population during spawning.