BACTERIAL LIPOPEPTIDES INDUCE ION-CONDUCTING PORES IN PLANAR BILAYERS

BACTERIAL LIPOPEPTIDES INDUCE ION-CONDUCTING PORES IN PLANAR BILAYERS
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DOI:
10.1016/0006-291x(85)91985-0
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发表时间:
1985-01-01
影响因子:
3.1
通讯作者:
GUINAND, M
GUINAND, M
中科院分区:
生物学4区
文献类型:
--
作者:
MAGETDANA, R;HEITZ, F;GUINAND, M

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细菌脂肽以其抗生素活性而闻名,对其与脂膜相互作用的能力进行了测试。这些类似的结构特征:七肽循环与烃链相连。证据表明这些脂肽通过形成离子传导孔来改变平面双层的电导。
Bacterial lipopeptides, known for their antibiotic activities, were tested for their ability to interact with lipid membranes. These analogous structural characteristics: a heptapeptidic cycle is linked to a hydrocarbon chain. Evidence that these lipopeptides modify the conductance of planar bilayers by forming ion-conducting pores is presented.