Two novel retron elements are replaced with retron-Vc95 in Vibrio cholerae

Two novel retron elements are replaced with retron-Vc95 in Vibrio cholerae
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DOI:
10.1111/j.1348-0421.2011.00342.x
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发表时间:
2011-07-01
影响因子:
2.6
通讯作者:
Shimamoto, Tadashi
Shimamoto, Tadashi
中科院分区:
医学4区
文献类型:
--
作者:
Inouye, Kumiko;Tanimoto, Saori;Shimamoto, Tadashi

文献摘要

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细菌逆转录酶(RT)负责产生称为多拷贝单链DNA(msDNA)的RNA-DNA复合物。合成msDNA所需的遗传元件称为retron。在这里,我们描述了两个新的retrons命名为retron-Vc 81和retron-Vc 137霍乱弧菌。有趣的是,在染色体上的相同位置,retron-Vc 81和retron-Vc 137被retron-Vc 95取代。
Bacterial reverse transcriptase (RT) is responsible for the production of an RNA-DNA complex called multicopy single-stranded DNA (msDNA). The genetic element required for the sysnthesis of msDNA is named a retron. Here, we characterize two novel retrons named retron-Vc81 and retron-Vc137 in Vibrio cholerae. Interestingly, retron-Vc81 and retron-Vc137 are replaced by retron-Vc95 at the same location on the chromosome.