Linear, redox modified DNA probes as electrochemical DNA sensors
Linear, redox modified DNA probes as electrochemical DNA sensors
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DOI：
10.1039/b708882e
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发表时间：
2007-01-01
影响因子：
4.9
通讯作者：
Plaxco, Kevin W.
中科院分区：
文献类型：
--
作者：
Ricci, Francesco;Lai, Rebecca Y.;Plaxco, Kevin W.
我们在这里表明，氧化还原修饰的电极结合线性（与茎环相反）探针DNA的动力学变化与杂交相关，会产生法拉第电流的巨大变化，从而可以随时检测到目标寡核苷酸。
We show here that hybridization-linked changes in the dynamics of a redox-modified, electrode-bound linear ( as opposed to stem-loop) probe DNA produce large changes in Faradaic current, allowing for the ready detection of target oligonucleotides.