Growing applications and advancements in microarray technology and analysis tools
Growing applications and advancements in microarray technology and analysis tools
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DOI：
10.1385/cbb:43:1:149
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发表时间：
2005-01-01
影响因子：
2.6
通讯作者：
Van der Spek, P
中科院分区：
文献类型：
--
作者：
Peeters, JK;Van der Spek, P
在当今的基因组学领域，传统的逐个基因的方法已不足以满足处理人类基因组复杂生物学图谱所产生的信息的需求。更全面地分析信息量是必要的，比如用微阵列。如今，微阵列技术正在迅速揭示遗传活动的广泛模式，并展示对基因功能、过程和途径的洞察。随着技术的发展，即将出现的知识正在从许多不同的生物体和系统发育中寻找转录过程和生物学机制。正在开发许多工具来协助分析这种高通量数据，许多应用程序正在利用这项技术，该领域正在迅速发展和扩大，以适应不断扩大的基因组学时代。
In today's field of genomics, traditional gene-by-gene approach is not adequate to meet the demand of processing information generated from mapping the complex biology of the human genome. More global views of analyzing the magnitude of information are necessary, such as with microarrays. Microarray technology today is rapidly uncovering broad patterns of genetic activity and showing insight into gene functions, processes, and pathways. With the growing technology, imminent knowledge is being generated looking into transcriptional processes and biological mechanisms from many different organisms and phylogeny. Many tools are being developed to assist with the analysis of such high-throughput data, many applications are being utilized by this technology, and the field is growing and expanding rapidly to accommodate the expanding genomics era.