Depressive symptomatology during pregnancy: Evidence for an association with decreased fetal growth in pregnancies of lower social class women
Depressive symptomatology during pregnancy: Evidence for an association with decreased fetal growth in pregnancies of lower social class women
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DOI：
10.1037/0278-6133.19.6.535
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发表时间：
2000-11-01
影响因子：
4.2
通讯作者：
Hatch, MC
中科院分区：
文献类型：
--
作者：
Hoffman, S;Hatch, MC
在 666 名孕妇中评估了流行病学研究中心抑郁量表（CES-D；L.S.Radloff，1977）在怀孕每个三个月的抑郁症状评分与胎儿生长或妊娠持续时间减少之间的关系。总体上没有关联，但在 222 名来自较低职业地位家庭的女性中，妊娠 28 周时 CES-D 每增加一个单位，与胎龄调整出生体重减少 9.1 克（95% 置信区间 [CI] = -16.0, -2.3）相关。当对缺失数据进行多重插补时，估计值为-4.6 g (95% CI = -10.7, 1.5)。在其他潜在高风险亚组（吸烟者、有不良结局史的女性以及有社会脆弱性的女性）的分析中，CES-D 评分与胎儿生长或妊娠持续时间无关。这些结果表明，在地位较低的女性中，抑郁情绪可能与胎儿生长受限有关。
The relationship between depressive symptom scores on the Center for Epidemiological Studies Depression Scale (CES-D; L. S. Radloff, 1977) at each trimester of pregnancy and a decrement in either fetal growth or gestational duration was evaluated among 666 pregnant women. There was no association overall, but among 222 women from lower occupational status households, each unit increase on the CES-D at 28 weeks gestation was associated with a reduction of 9.1 g (95% confidence interval [CI] = -16.0, -2.3) in gestational-age-adjusted birth weight. When missing data were multiply imputed, the estimate was -4.6 g (95% CI = -10.7, 1.5). CES-D score was unrelated to fetal growth or gestational duration in analyses among other potentially high-risk subgroups: smokers, women with a history of adverse outcome, and women with social vulnerabilities. These results raise the possibility that among lower status women, depressive mood may be associated with restricted fetal growth.