Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005-2009
Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005-2009
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DOI：
10.1111/j.1528-1167.2010.02522.x
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发表时间：
2010-04-01
期刊：
影响因子：
5.6
通讯作者：
Scheffer, Ingrid E.
中科院分区：
文献类型：
--
作者：
Berg, Anne T.;Berkovic, Samuel F.;Scheffer, Ingrid E.
国际抗癫痫联盟（ILAE）分类和术语委员会修订了癫痫发作和癫痫形式分类的概念、术语和方法。全身性和局灶性癫痫发作被重新定义为在双边分布的网络中发生并迅速参与（全身性）和在局限于一个半球的网络内发生，或者分散局部化，或者分布更广（局灶性）。全身性发作的分类被简化。局灶性癫痫发作没有自然分类;局灶性癫痫发作应根据其表现（例如，认知障碍、局灶性运动）。全身性和局灶性的概念不适用于电临床综合征。遗传、结构-代谢和未知代表修改后的概念，以取代特发性、症状性和隐源性。并非所有癫痫都被认为是电临床综合征。癫痫的类型首先按特异性分类：电临床综合征、结构-代谢原因引起的非综合征性癫痫和原因不明的癫痫。这些部门内的进一步组织可以根据目的以灵活的方式完成。自然类（例如，具体的潜在原因、发病年龄、相关的癫痫发作类型），或实用分组（例如，癫痫性脑病、自限性电临床综合征）可以作为组织关于公认形式的癫痫的知识的基础，并促进新形式的识别。
P>The International League Against Epilepsy (ILAE) Commission on Classification and Terminology has revised concepts, terminology, and approaches for classifying seizures and forms of epilepsy. Generalized and focal are redefined for seizures as occurring in and rapidly engaging bilaterally distributed networks (generalized) and within networks limited to one hemisphere and either discretely localized or more widely distributed (focal). Classification of generalized seizures is simplified. No natural classification for focal seizures exists; focal seizures should be described according to their manifestations (e.g., dyscognitive, focal motor). The concepts of generalized and focal do not apply to electroclinical syndromes. Genetic, structural-metabolic, and unknown represent modified concepts to replace idiopathic, symptomatic, and cryptogenic. Not all epilepsies are recognized as electroclinical syndromes. Organization of forms of epilepsy is first by specificity: electroclinical syndromes, nonsyndromic epilepsies with structural-metabolic causes, and epilepsies of unknown cause. Further organization within these divisions can be accomplished in a flexible manner depending on purpose. Natural classes (e.g., specific underlying cause, age at onset, associated seizure type), or pragmatic groupings (e.g., epileptic encephalopathies, self-limited electroclinical syndromes) may serve as the basis for organizing knowledge about recognized forms of epilepsy and facilitate identification of new forms.