Transmission dynamics of a zoonotic pathogen within and between wildlife host species
Transmission dynamics of a zoonotic pathogen within and between wildlife host species
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DOI：
10.1098/rspb.1999.0870
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发表时间：
1999-10-07
影响因子：
4.7
通讯作者：
Bennett, M
中科院分区：
文献类型：
--
作者：
Begon, M;Hazel, SM;Bennett, M
牛痘病毒感染的传播动力学已被量化的两个混合种群的银行田鼠（Clethrionomys glareolus）和木鼠（Apodemus sylvaticus），通过详细的时间序列的易感，传染性和新感染的个人的数量分析。牛痘病毒是一种人畜共患病，在这些啮齿动物宿主中传播，并已被证明对生殖输出有不利影响。物种内的传输动力学最好描述为频率依赖，而不是密度依赖，相反的“质量作用”的假设，大多数以前的研究，无论是理论还是经验。估计每个种群中每个物种的传播系数还可以通过分析回归残差来研究传播动态的年度和季节变化。尽管宿主物种密切共存，但它们之间的传播被认为是微不足道的。这对于作为人畜共患病水库的主机的结合能力的后果，并为主机之间的明显竞争，进行了讨论。
The transmission dynamics of the cowpox virus infection have been quantified in two mixed populations of bank voles (Clethrionomys glareolus) and wood mice (Apodemus sylvaticus), through analyses of detailed time-series of the numbers of susceptible, infectious and newly infected individuals. The cowpox virus is a zoonosis which circulates in these rodent hosts and has been shown to have an adverse effect on reproductive output. The transmission dynamics within species is best described as frequency dependent rather than density dependent, contrary to the 'mass action' assumption of most previous studies, both theoretical and empirical. Estimation of a transmission coefficient for each species in each population also allows annual and seasonal variations in transmission dynamics to be investigated through an analysis of regression residuals. Transmission between host species is found to be negligible despite their close cohabitation. The consequences of this for the combining ability of hosts as zoonotic reservoirs, and for apparent competition between hosts, are discussed.