Oncocytoma of the caruncle: a case report and ultrastructural study.
Oncocytoma of the caruncle: a case report and ultrastructural study.
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肉阜嗜酸细胞瘤：病例报告和超微结构研究。
DOI：
10.1097/00003226-199103000-00015
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发表时间：
1991
期刊：
影响因子：
2.8
通讯作者：
Leibowitz,HM
中科院分区：
文献类型：
--
作者：
Freddo,TF;Leibowitz,HM
本文报告1例泪阜嗜酸细胞瘤，并对手术标本进行了广泛的超微结构观察。单个瘤细胞呈柱状，顶端表面有微绒毛。它们的细胞质中充满了两种类型的线粒体。大多数是非常大的和卵圆形的嵴排列在广泛的模式。少数线粒体细长，嵴较典型。在少数大线粒体中发现了两种类型的颗粒状内含物，推测它们代表α-和β-糖原沉积物。低分化桥粒连接相邻的癌细胞的侧面。在某些情况下，这些连接有线粒体附着在其细胞质表面。本文比较了肉阜与其他部位癌细胞的超微结构特征。线粒体和桥粒，主要发生在分泌上皮细胞之间的关系，也进行了讨论。
A case of oncocytoma of the lacrimal caruncle is reported, in which extensive ultrastructural studies were completed on the surgical specimen. Individual oncocytes were columnar in shape with apical surface microvilli. Their cytoplasm was filled with two types of mitochondria. Most were very large and ovoid with cristae arranged in a wide array of patterns. A smaller number of mitochondria were long and slender with more typical cristae. Two types of granular inclusions, presumed to represent a-and ([beta]-glycogen deposits, were found within a small number of the large mitochondria. Poorly differentiated desmosomes joined the lateral surfaces of adjacent oncocytes. In some cases, these junctions had mitochondria attached to their cytoplasmic surfaces. A comparison is made between ultrastructural features of oncocytes in the caruncle and those found elsewhere. The relationship noted between mitochondria and desmosomes, which occurs predominantly in secretory epithelia, is also discussed.