Putative measure of peripheral and brainstem frequency-following in humans
Putative measure of peripheral and brainstem frequency-following in humans
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DOI：
10.1016/s0304-3940(00)01436-1
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发表时间：
2000-10-06
影响因子：
2.5
通讯作者：
Cheung, L
中科院分区：
文献类型：
--
作者：
Galbraith, GC;Threadgill, MR;Cheung, L
人类脑干频率跟随反应(FFR)记录对周期性听觉刺激的锁相神经活动。通过平均对重复听觉刺激的反应，从脑电中提取FFR波形。从水平(将电极放置在耳道中)和垂直(顶点头皮参考中线)定向电极配置同时记录两个通道的数据。八名参与者每人接受了总共2000次音调重复，每个刺激频率从133赫兹到950赫兹不等。FFR用快速傅立叶光谱分析进行定量。水平FFR在刺激频率处记录到的光谱强度最大，它也跟随较高的频率，显示出比垂直FFR更好的信噪比。水平的FFR模式提示听神经起源，而垂直的FFR模式提示中枢脑干起源。(C)2000爱思唯尔爱尔兰科学有限公司保留所有权利。
The human brainstem frequency-following response (FFR) registers phase-locked neural activity to periodic auditory stimuli. FFR waveforms were extracted from the electroencephalogram by averaging responses to repeated auditory stimulation. Two channels of data were simultaneously recorded from horizontally (electrodes placed in ear canals) and vertically (vertex scalp referenced to midline) oriented electrode configurations. Eight participants each received a total of 2000 tone repetitions for each of ten stimulus frequencies ranging from 133 to 950 Hz. FFRs were quantified by fast-Fourier spectral analysis. The largest spectral intensities at the stimulus frequency were recorded in the horizontal FFR, which also followed higher frequencies and showed better signal to-noise ratios then did the vertical FFR. The horizontal FFR pattern suggests an acoustic nerve origin, while the vertical FFR pattern suggests a central brainstem origin. (C) 2000 Elsevier Science Ireland Ltd. Ail rights reserved.