Prevalence of premature ventricular contractions in a population of African American and white men and women: The Atherosclerosis Risk in Communities (ARIC) Study
Prevalence of premature ventricular contractions in a population of African American and white men and women: The Atherosclerosis Risk in Communities (ARIC) Study
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DOI：
10.1067/mhj.2002.120298
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发表时间：
2002-03-01
影响因子：
4.8
通讯作者：
Heiss, G
中科院分区：
文献类型：
--
作者：
Simpson, RJ;Cascio, WE;Heiss, G
背景：室性早搏(PVCs)在不同人群中的分布或原因尚不完全清楚。我们描述了成年人2分钟心电图上的静脉曲张患病率，以确定高血压是否与此类静脉曲张有重要关联。方法对来自美国四个社区的15,792人(年龄45-65岁)进行横断面分析，这些人参加了社区动脉粥样硬化风险(ARIC)研究的访问1。结果：基于2分钟的心电图，6%的中年人存在门静脉高压症。年龄增长、心脏病的存在、窦性心率加快、非裔美国人种族、男性、低教育程度以及低血清镁或钾水平与PVC患病率直接相关。不考虑这些因素，高血压与室上性心动过速的患病率增加23%有关。结论2分钟心电图上的室上性早搏的患病率随年龄、种族和性别的不同而不同，并与高血压、心脏病、窦性心率加快、电解质异常和低教育程度有关。高血压很可能是成人静脉曲张的主要原因。
Background The distribution or the causes of premature ventricular contractions (PVCs) in diverse populations are not fully known. We describe the prevalence of PVCs on a 2-minute electrocardiogram (ECG) in adults to determine whether hypertension has an important association with such PVCs.Methods A cross-sectional analysis of the 15,792 individuals (aged 45-65 years) from the four US communities participating at visit 1 of the Atherosclerosis Risk In Communities (ARIC) study was performed. Multiple logistic regression was used to determine the association of PVCs with potential causal predictors of PVCs.Results Based on a 2-minute ECG, PVCs are present in >6% of middle-aged adults. Increasing age, the presence of heart disease, faster sinus rates, African American ethnicity, male sex, lower educational attainment, and lower serum magnesium or potassium levels are directly related to PVC prevalence. Independently of these factors, hypertension is associated with a 23% increase in the prevalence of PVCs.Conclusions The prevalence of PVCs on a 2-minute ECG differs by age, ethnicity, and sex and is associated with hypertension, heart disease, faster sinus rates, electrolyte abnormalities, and lower educational attainment. Hypertension is likely to be a major cause of PVCs in adults.