Biooxidation of 7,12-dimethylbenz[a]anthracene in rat subcutaneous tissue.
Biooxidation of 7,12-dimethylbenz[a]anthracene in rat subcutaneous tissue.
复制标题
7,12-二甲基苯并[a]蒽在大鼠皮下组织中的生物氧化。
DOI:
10.1016/0006-2952(89)90614-x
复制
发表时间:
1989
影响因子:
5.8
通讯作者:
Flesher,JW
中科院分区:
文献类型:
--
作者:
Myers,SR;Flesher,JW
The present study demonstrates the biooxidation of 7,12-dimethylbenz[a]anthracene to the corresponding hydroxyalkyi metabolites, 7-hydroxymethylbenz[a]anthracene, 7-hydroxymethyl-12-methylbenz[a] anthracene, and 7,12-dihydroxymethylbenz[a]anthracene in the dorsal subcutaneous tissue of the rat,in vivo, a tissue highly susceptible to the carcinogenic action of 7,12-dimethylbenz[a] anthracene.