Abdominal respiration induces hemodilution and related reduction in ADH concentration of blood.
Abdominal respiration induces hemodilution and related reduction in ADH concentration of blood.
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腹式呼吸引起血液稀释并导致血液中 ADH 浓度降低。
DOI：
10.1089/lrb.2015.0017
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Nagai T et al
中科院分区：
文献类型：
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作者：
Kawai Y;Ajima K;Nagai T et al
为了建立有效的淋巴引流方法，并开发简洁准确的临床技术，用于评估健康个体和癌症治疗相关淋巴水肿患者的淋巴引流，我们研究了血液中红细胞（RBC）和白色（WBC）细胞的数量，血小板（PLT），红细胞压积（Ht），以及血液中总蛋白（TP），白蛋白（Alb），48名健康志愿者在仰卧位或坐位下，经手法淋巴引流5min，然后休息30min，进行腹式呼吸或不进行腹式呼吸，观察引流前后血浆抗利尿激素（ADH）的变化。5分钟的面部，上肢和下肢淋巴引流，然后在仰卧位休息30分钟，诱导所有受试者的TP和Alb显著降低，部分受试者的RBC和Ht水平显著降低。仅在仰卧位休息30分钟，无淋巴引流，也产生了显着减少血液TP和ALB。此外，腹式呼吸仰卧位无手动淋巴引流造成更显着的血液稀释，显着减少TP，ALB，RBC，Ht，ADH在所有志愿者。这些发现可能与乳糜囊肿的有效淋巴引流有关。此外，它还导致排尿欲望显著增加。总之，仰卧位休息30分钟期间的腹式呼吸可有效诱导淋巴引流，相关的血液稀释诱导和血液ADH浓度降低（以及某些情况下排尿欲望增加）可用于准确评估淋巴引流的程度。
To establish effective lymph drainage methods and develop concise and accurate clinical techniques for evaluating lymph drainage in healthy individuals and patients with cancer treatment-related lymph edema, we investigated the numbers of red (RBC) and white (WBC) blood cells, and platelets (PLT) in blood, hematocrit (Ht), and the blood concentrations of total protein (TP), albumin (Alb), and anti-diuretic hormone (ADH) before and after 5 min manual lymph drainage, followed by 30 min rest with or without abdominal respiration in the supine or sitting position in 48 healthy volunteers. The 5 min facial, upper and lower extremities lymph drainage, followed by 30 min rest in the supine position induced significant reductions of the TP and Alb in all subjects, and their RBC and Ht levels in some subjects. The 30 min rest only in the supine position without lymph drainage produced also significant reductions of blood TP and Alb. In addition, abdominal respiration in the supine position without manual lymph drainage caused more significant hemodilution, being significant reductions of TP, Alb, RBC, Ht, and ADH in all volunteers. These findings may be related to effective lymph drainage from the chylocyst. Furthermore, it also resulted in a significantly increased micturition desire. In conclusion, abdominal respiration during 30 min rest in the supine position is effective at inducing lymph drainage, and the associated induction of hemodilution and lowering of the blood ADH concentration (and increased micturition desire in some cases) can be used to accurately assess the extent of lymph drainage.