Human herpesvirus 6 infection associated with anticonvulsant hypersensitivity syndrome and reactive haemophagocytic syndrome
Human herpesvirus 6 infection associated with anticonvulsant hypersensitivity syndrome and reactive haemophagocytic syndrome
复制标题
DOI：
10.1111/j.1365-2133.1997.tb03795.x
复制
发表时间：
1997-10-01
影响因子：
10.3
通讯作者：
Belaich, S
中科院分区：
文献类型：
--
作者：
Descamps, V;Bouscarat, F;Belaich, S
病毒感染被认为与某些皮肤药物反应有关，而人类疱疹病毒 6 (HHV6) 是引起皮疹（第六种疾病）的病原体，但从未与药物反应有关。我们报告了一名患有严重苯巴比妥诱发的抗惊厥过敏综合征的患者，其中暴发性噬血细胞综合征与 HHV6 感染相关。我们讨论了 HHV6 在这种反应条件下的可能作用。
Viral infections are thought to play a part in some cutaneous drug reactions, Human herpesvirus 6 (HHV6), which is the agent of exanthema subitum (sixth disease), has never been implicated in a drug reaction. We report a patient with severe phenobarbital-induced anticonvulsant hypersensitivity syndrome in whom a fulminant haemophagocytic syndrome was associated with HHV6 infection. We discuss the possible role of HHV6 in this reactive condition.