Effects of One-Lung Ventilation on Cardiac Autonomic Nervous Activity as Evaluated by Power Spectral Analysis of Heart Rate Variability
Effects of One-Lung Ventilation on Cardiac Autonomic Nervous Activity as Evaluated by Power Spectral Analysis of Heart Rate Variability
复制标题
通过心率变异性功率谱分析评估单肺通气对心脏自主神经活动的影响
DOI：
10.1023/a:1009963414619
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发表时间：
2004
影响因子：
2.2
通讯作者：
Keisuke Inoue
中科院分区：
文献类型：
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作者：
N. Sato;M. Kawamoto;O. Yuge,;M. Sanuki;C. Matsumoto;Keisuke Inoue
本前瞻性研究的目的是评估单肺通气对心脏自主神经系统活动的影响。10例行开胸手术的成人患者在异氟醚全麻下经气管内双腔管插管。麻醉诱导后，在双侧肺通气（对照组）期间连续记录256秒心电图（ECG），然后在每侧单肺通气期间记录心电图。利用256秒心电图的R-R间隔图，利用快速傅立叶变换算法对低频（LF: 0.04 ~ 0.15Hz）和高频（HF: 0.15 ~ 0.40 Hz）频段的心率变异性谱密度和HF/LF比值进行分析。指示副交感神经活动的Log（HF）在单肺通气时每侧均增加，但通气侧间无差异。代表交感神经和副交感神经活动的Log（LF）与Log（HF）在双侧相似地增加，而代表交感神经和副交感神经活动平衡的Log（HF/LF）在单肺通气期间没有改变。我们认为单肺通气不会对心脏自主神经系统产生实质性影响。
The purpose of this prospective study was to evaluate the effects ofone-lung ventilation on the activity of the cardiac autonomic nervous system.Ten adult patients who underwent thoracotomy were endotracheally intubatedwith a double-lumen tube under general anesthesia using isoflurane. Afterinduction of anesthesia, a continuous, 256-sec electrocardiogram (ECG) wasobtained during bilateral lung ventilation (control) followed by recordingsduring one-lung ventilation of each side. Using the R–R intervaltachograms obtained for the 256-sec ECGs, low frequency (LF: 0.04–0.15Hz) and high frequency (HF: 0.15–0.40 Hz) bands of the spectral densityof the heart rate variability and the HF/LF ratio were analyzed using the fastFourier transform algorithm. Log(HF), which indicates parasympatheticactivity, increased during one-lung ventilation on each side, but did notdiffer between ventilated sides. Log(LF), which represents sympathetic andparasympathetic activity, increased similarly to log(HF) on both sides.Log(HF/LF), the balance of the sympathetic and parasympathetic activity, didnot change during one-lung ventilation. We suggest that one-lung ventilationalone does not substantially affect the cardiac autonomic nervous system.