Synaptic transmission from rods to bipolar cells in the tiger salamander retina.
Synaptic transmission from rods to bipolar cells in the tiger salamander retina.
复制标题
虎蝾螈视网膜中从视杆细胞到双极细胞的突触传递。
DOI：
10.1073/pnas.82.11.3944
复制
发表时间：
1985
影响因子：
11.1
通讯作者：
Wu,SM
中科院分区：
文献类型：
--
作者：
Wu,SM
在活体视网膜切片上，用同步记录技术研究了视杆细胞与去极化双极细胞（DBC）之间的突触传递。电流注入杆引起了一个符号反转，持续的电压变化的DBC。电压“尾巴”终止后，明亮的闪光观察到暗适应杆和DBC，但不是在锥。这些同时记录的电压尾被用来分离视杆细胞输入和视锥细胞输入，并研究视杆细胞-DBC突触的输入-输出关系。在离视杆暗电位（-39 +/-1.2 mV）0和-10 mV之间的电压范围内，视杆-DBC的输入-输出关系近似线性，估计增益约为3.7。
Synaptic transmission between rods and depolarizing bipolar cells (DBC) was studied by using simultaneous recording techniques in the living retinal slice preparation. Current injection into the rod elicited a sign-inverting, sustained voltage change in the DBC. Voltage "tails" after the termination of a bright flash were observed in dark-adapted rods and DBC but not in cones. These simultaneously recorded voltage tails were used to isolate the rod input from the cone input and to study the input-output relation of the rod-DBC synapse. Within the voltage range between 0 and -10 mV from the rod dark potential (-39 +/- 1.2 mV), the input-output relation of the rod-DBC was approximately linear, with an estimated gain of about 3.7.