Electroencephalography in the Early Diagnosis of HIV-Related Subacute Encephalitis: Analysis of 185 Patients
Electroencephalography in the Early Diagnosis of HIV-Related Subacute Encephalitis: Analysis of 185 Patients
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脑电图在 HIV 相关亚急性脑炎早期诊断中的应用：185 例患者分析
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
G. Nappi
中科院分区：
文献类型：
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作者：
A. Parisi;Maurizio Strosselli;G. di Perri;Silvano Cairoli;L. Minoli;G. Bono;A. Moglia;G. Nappi
对185例无症状HIV感染者或腺病综合征患者进行了脑电图计算机频谱分析和绘图（EEG-CSA）研究。在118例无症状感染患者（CDC II组）中有30例（25.4%）和67例腺病综合征患者（CDC III组）中有20例（29.9%）发现异常EEG。最常见的脑电图异常表现为额叶和额颞叶θ波减慢，在某些情况下，表现为前脑δ波减慢和阵发性急剧活动。在50例脑电图异常的患者中，16例在神经心理学测试中表现出一定的异常，而只有12例患者在CT扫描中表现出轻微的脑萎缩迹象。这些结果表明，脑电图CSA可能是一个有用的和敏感的方法在早期发现和监测艾滋病毒相关的亚急性脑炎。
Of subjects with asymptomatic HIV infection or Lymphoadenopathy Syndrome, 185 were studied by means of electroencephalography coupled with computerized spectral analysis and mapping (EEG-CSA). Abnormal EEGs were found in 30 of 118 (25.4%) patients with asymptomatic infection (CDC Group II) and in 20 of 67 (29.9%) patients with Lymphoadenopathy Syndrome (CDC Group III). The most common EEG abnormalities were represented by theta slowing on the frontal and fronto-temporal lobes and, in some cases, by delta slowing and paroxysmal sharp activity on the forebrain. Among 50 patients with abnormal EEGs, 16 showed some abnormalities on neuropsychological testing, whereas mild signs of cerebral atrophy were evident on CT scan in only 12 patients. These findings suggest that EEG-CSA could be a useful and sensitive method in the early detection and monitoring of HIV-related subacute encephalitis.
影响因子：
39.2
作者：
GABUZDA, DH;HIRSCH, MS
通讯作者：
HIRSCH, MS