Blood glucose concentrations ≤ 125 mg/dl and coronary heart disease risk
Blood glucose concentrations ≤ 125 mg/dl and coronary heart disease risk
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DOI：
10.1016/s0002-9149(01)02302-5
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发表时间：
2002-03-01
影响因子：
2.8
通讯作者：
Vidt, DG
中科院分区：
文献类型：
--
作者：
Hoogwerf, BJ;Sprecher, DL;Vidt, DG
这项研究试图确定空腹血糖水平，冠心病（CHD）危险因素和冠心病的患病率之间的关系，在一个高风险组的患者参加心脏病预防诊所。本研究旨在解决两个问题。(1)非糖尿病范围内的空腹血糖浓度升高（小于或等于125 mg/dl）是否与传统（吸烟、中心性肥胖、全身性高血压、血脂异常）和非传统（例如，纤维蛋白原、同型半胱氨酸、脂蛋白（a）[Lp（a）]）冠心病危险因素？(2)在此范围内血糖浓度升高是否与独立于这些风险因素的CHD的持续和分级风险相关？
T his study sought to determine the relation between fasting glucose levels, coronary heart disease (CHD) risk factors, and the prevalence of CHD in a high-risk group of patients attending a cardiology prevention clinic. The study was designed to address 2 questions. (1) Are increasing fasting glucose concentrations in the nondiabetic range (less than or equal to125 mg/dl) associated with an increased burden of traditional (smoking, central obesity, systemic hypertension, dyslipidemia) and nontraditional (e.g., fibrinogen, homocysteine, lipoprotein(a) [Lp(a)]) CHD risk factors? (2) Are increasing blood glucose concentrations in this range associated with a continuous and graded risk for CHD independent of these risk factors?.