Modeling and Analyzing Biomedical Processes using Workflow/Petri Net Models and Tools

Modeling and Analyzing Biomedical Processes using Workflow/Petri Net Models and Tools
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使用工作流/Petri 网模型和工具对生物医学过程进行建模和分析

DOI:
10.3233/978-1-60750-949-3-74
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发表时间:
2004
影响因子:
--
通讯作者:
R. Altman
R. Altman
中科院分区:
--
文献类型:
--
作者:
M. Peleg;S. Tu;Abhijit Manindroo;R. Altman

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计算机仿真使系统开发人员能够在计算机上执行实际或理论系统的模型,并分析执行输出。我们一直在探索使用Petri网(PN)工具来研究使用三种生物医学模型表示的系统的行为:用于表示生物过程的生物工作流模型,以及来自临床指南的两种不同的计算机可解释的医疗保健过程模型。我们开发并实现了将三个模型映射到单个底层流程模型(工作流)的软件,然后将其转换为PN,其格式可由几个PN模拟和分析工具读取。这些分析工具使我们能够模拟和研究两个生物医学系统的行为:侵入宿主细胞的疟疾寄生虫和正在接受慢性咳嗽管理的患者。
Computer simulation enables system developers to execute a model of an actual or theoretical system on a computer and analyze the execution output. We have been exploring the use of Petri Net (PN) tools to study the behavior of systems that are represented using three kinds of biomedical models: a biological workflow model used to represent biological processes, and two different computer-interpretable models of health care processes that are derived from clinical guidelines. We developed and implemented software that maps the three models into a single underlying process model (workflow), which is then converted into PNs in formats that are readable by several PN simulation and analysis tools. These analysis tools enabled us to simulate and study the behavior of two biomedical systems: a Malaria parasite invading a host cell, and patients undergoing management of chronic cough.
DOI: --
发表时间: 2000
期刊: Proceedings. AMIA Symposium
影响因子: --
作者:
M. Peleg;A. Boxwala;O. Ogunyemi;Qing Zeng-Treitler;S. Tu;Ronilda C. Lacson;E. Bernstam;N. Ash;P. Mork;L. Ohno-Machado;E. Shortliffe;R. Greenes
通讯作者: M. Peleg;A. Boxwala;O. Ogunyemi;Qing Zeng-Treitler;S. Tu;Ronilda C. Lacson;E. Bernstam;N. Ash;P. Mork;L. Ohno-Machado;E. Shortliffe;R. Greenes
DOI: --
发表时间: 2003
期刊: AMIA ... Annual Symposium proceedings. AMIA Symposium
影响因子: --
作者:
Tu,SamsonW;Campbell,James;Musen,MarkA
通讯作者: Musen,MarkA
DOI: 10.1197/jamia.m1135
发表时间: 2003-01-01
影响因子: 6.4
作者:
Peleg, M;Tu, S;Stefanelli, M
通讯作者: Stefanelli, M