FLUOROSCOPIC AND COMPUTED TOMOGRAPHIC FEATURES OF THE PHARYNGEAL AIRWAY IN OBSTRUCTIVE SLEEP-APNEA

FLUOROSCOPIC AND COMPUTED TOMOGRAPHIC FEATURES OF THE PHARYNGEAL AIRWAY IN OBSTRUCTIVE SLEEP-APNEA
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DOI:
10.1164/arrd.1983.127.4.487
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发表时间:
1983-01-01
期刊:
AMERICAN REVIEW OF RESPIRATORY DISEASE
影响因子:
--
通讯作者:
WILHOIT, SC
WILHOIT, SC
中科院分区:
其他
文献类型:
--
作者:
SURATT, PM;DEE, P;WILHOIT, SC

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由于有研究表明阻塞性睡眠呼吸暂停患者的咽部呼吸道较正常人狭窄,因此对该综合征患者进行了侧位透视和咽部CT扫描。6例睡眠患者透视显示,阻塞多始于吸气时,即软腭触碰到舌头及咽后壁。9例清醒受试者的CT扫描显示,患者和对照组的呼吸道最窄的部分是软腭部后面的区域。患者组这一区域的横截面积明显小于对照组(P<0.001)。由于狭窄的气道在吸气时比正常的更容易塌陷(伯努利的S原理),清醒患者观察到的狭窄的气道可能是阻塞性睡眠呼吸暂停的重要致病因素。
Because it has been suggested that patients with obstructive sleep apnea have a narrower pharyngeal airway than normal persons, lateral fluoroscopy and computed tomographic (CT) scans of the pharynx were performed in patients with this syndrome. Fluoroscopy in 6 sleeping patients showed that the obstruction always began during inspiration when the soft palate touched the tongue and posterior pharyngeal wall. The CT scans in 9 awake subjects demonstrated that the narrowest section of the airway in patients and in control subjects was the region posterior to the soft palate. The cross-sectional area of this region was significantly narrower in patients than it was in control subjects (P < 0.001). Because a narrow airway would be more likely to collapse during inspiration than a normal one would (Bernoulli''s Principle), the narrow airways observed in awake patients may be an important contributing factor in the pathogenesis of obstructive sleep apnea.